Synapse - Dongfang Meng

Results (17)

Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines

Journal Article

Martello, L. A.; McDaid, H. M.; Regl, D. L.; Yang, C. H.; Meng, D.; Pettus, T. R. R.; Kaufman, M. D.; Arimoto, H.; Danishefsky, S. J.; Smith, A. B. 3rd; more...
Clinical Cancer Research (2000)

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The microtubule-stabilizing agents epothilones A and B and their desoxy- derivatives induce mitotic arrest and apoptosis in human prostate cancer cells

Journal Article

Sepp-Lorenzino, L.; Balog, A.; Su, D. S.; Meng, D.; Timaul, N.; Scher, H. I.; Danishefsky, S. J.; Rosen, N.
Prostate Cancer and Prostatic Diseases (1999)

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Stereospecific sulfur-mediated cleavage of a spirocyclobutanone: Synthesis of a fully functional precursor to the CP compounds

Journal Article

Meng, D.; Danishefsky, S. J.
Angewandte Chemie - International Edition (1999)

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Discovery through total synthesis — Epimerization at C7 in the CP compounds: Is (7S)-CP-263,114 a fermentation product?

Journal Article

Meng, D.; Tan, Q.; Danishefsky, S. J.
Angewandte Chemie - International Edition (1999)

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A useful α,α '-annulation reaction of enamines

Journal Article

Frontier, A. J.; Danishefsky, S. J.; Koppel, G. A.; Meng, D.
Tetrahedron (1998)

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Desoxyepothilone B: An efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B

Journal Article

Chou, T. C.; Zhang, X. G.; Balog, A.; Su, D. S.; Meng, D.; Savin, K.; Bertino, J. R.; Danishefsky, S. J.
Proceedings of the National Academy of Sciences of the United States of America (1998)

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Total syntheses of CP-225,917 and CP-263,114: Creation of a matrix structure by sequential aldol condensation and intramolecular Heck ring closure

Journal Article

Kwon, O.; Su, D. S.; Meng, D.; Deng, W.; D'Amico, D. C.; Danishefsky, S. J.
Angewandte Chemie - International Edition (1998)

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A stereospecific geminal alkylation scheme en route to CP-225, 917 and CP-263,114

Journal Article

Kwon, O.; Su, D. S.; Meng, D.; Deng, W.; D'Amico, D. C.; Danishefsky, S. J.
Angewandte Chemie - International Edition (1998)

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Epothilones can substitute for taxol in cells dependent on taxol for growth

Meeting Abstract

He, L.; Martello, L.; Regl, D.; Horwitz, S. B.; Su, D. S.; Meng, D.; Balog, A.; Danishefsky, S. J.
Molecular Biology of the Cell (1997)

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Total syntheses of epothilones A and B

Journal Article

Meng, D.; Bertinato, P.; Balog, A.; Su, D. S.; Kamenecka, T.; Sorensen, E. J.; Danishefsky, S. J.
Journal of the American Chemical Society (1997)

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