A useful α,α '-annulation reaction of enamines Journal Article
| Authors: | Frontier, A. J.; Danishefsky, S. J.; Koppel, G. A.; Meng, D. |
| Article Title: | A useful α,α '-annulation reaction of enamines |
| Abstract: | The reactions of a series of enamines generated from a range of cyclic ketones with chloromethyl and iodomethyl vinyl ketone have been studied. The principal products are bridged ring diketones. The four carbon bridge, bearing a 2-oxobutyl function, spans the alpha and alpha' carbons of the original cyclanone. Presumptive evidence as to the pathway of this novel one step bridging annulation is provided. (C) 1998 Elsevier Science Ltd. All rights reserved. |
| Keywords: | addition reactions; annulation; cp-225,917; cyclisation; cp-263,114 |
| Journal Title: | Tetrahedron |
| Volume: | 54 |
| Issue: | 42 |
| ISSN: | 0040-4020 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1998-10-01 |
| Start Page: | 12721 |
| End Page: | 12736 |
| Language: | English |
| ACCESSION: | WOS:000076179100007 |
| DOI: | 10.1016/s0040-4020(98)00788-1 |
| PROVIDER: | wos |
| Notes: | Article -- Source: Wos |
