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Nonsynonymous single nucleotide polymorphisms in DNA damage repair pathways and lung cancer risk

Journal Article

Tanaka, Y.; Maniwa, Y.; Bermudez, V. P.; Doi, T.; Nishio, W.; Ohbayashi, C.; Okita, Y.; Hurwitz, J.; Hayashi, Y.; Yoshimura, M.
Cancer (2010)

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Multiplexed random peptide library and phospho-specific antibodies facilitate human polo-like kinase 1 inhibitor screen

Journal Article

Tanaka, K.; Koresawa, M.; Iida, M.; Fukasawa, K.; Stec, E.; Cassaday, J.; Chase, P.; Rickert, K.; Hodder, P.; Takagi, T.; more...
Assay and Drug Development Technologies (2010)

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A facile and efficient synthesis of d6-labeled PU-H71, a purine-scaffold Hsp90 inhibitor

Journal Article

Taldone, T.; Zatorska, D.; Kang, Y.; Chiosis, G.
Journal of Labelled Compounds and Radiopharmaceuticals (2010)

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Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90

Journal Article

Taldone, T.; Gillan, V.; Sun, W.; Rodina, A.; Patel, P.; Maitland, K.; O'Neill, K.; Chiosis, G.; Devaney, E.
PLoS Neglected Tropical Diseases (2010)

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Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

Journal Article

Takai, H.; Xie, Y.; De Lange, T.; Pavletich, N. P.
Genes and Development (2010)

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Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations

Journal Article

Singla, N.; Goldgur, Y.; Xu, K.; Paavilainen, S.; Nikolov, D. B.; Himanen, J. P.
Biochemical and Biophysical Research Communications (2010)

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Rho-kinase directs bazooka/Par-3 planar polarity during drosophila axis elongation

Journal Article

Simoes, S. d M.; Blankenship, J. T.; Weitz, O.; Farrell, D. L.; Tamada, M.; Fernandez-Gonzalez, R.; Zallen, J. A.
Developmental Cell (2010)

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Genetically engineered oncolytic newcastle disease virus effectively induces sustained remission of malignant pleural mesothelioma

Journal Article

Silberhumer, G. R.; Brader, P.; Wong, J.; Serganova, I. S.; Gonen, M.; González, S. J.; Blasberg, R.; Zamarin, D.; Fong, Y.
Molecular Cancer Therapeutics (2010)

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Empirical estimates of the lead time distribution for prostate cancer based on two independent representative cohorts of men not subject to prostate-specific antigen screening

Journal Article

Savage, C. J.; Lilja, H.; Cronin, A. M.; Ulmert, D.; Vickers, A. J.
Cancer Epidemiology Biomarkers and Prevention (2010)

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Genome destabilization by homologous recombination in the germ line

Journal Article

Sasaki, M.; Lange, J.; Keeney, S.
Nature Reviews Molecular Cell Biology (2010)

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