T cell responses to Listeria monocytogenes Journal Article
| Authors: | Lara-Tejero, M.; Pamer, E. G. |
| Article Title: | T cell responses to Listeria monocytogenes |
| Abstract: | Owing to its unique intracellular biology that allows it to gain access to the host cell cytosol, Listeria monocytogenes induces potent, protective CD8 responses. The study of these responses has served as a paradigm to understand cell-mediated immunity to microbial pathogens. The availability of mutants specifically defective in unique aspects of the intracellular biology of this pathogen has greatly aided these studies. During the past few years, progress has been made to understand the contribution of the innate immune system and CD4 T cells in the generation of robust, long lasting CD8 responses to L. monocytogenes. |
| Keywords: | signal transduction; protein expression; clinical trial; review; nonhuman; side effect; cd8 antigen; cell proliferation; t lymphocyte; t-lymphocytes; animals; dendritic cell; cell differentiation; bacteria (microorganisms); t lymphocyte receptor; antigen presentation; cellular immunity; gamma interferon; tissue distribution; major histocompatibility antigen class 2; cytotoxic t lymphocyte; virus antigen; cd4 antigen; macrophage; memory cell; beta interferon; antigen presenting cell; myeloid differentiation factor 88; toll like receptor; infection sensitivity; listeriosis; listeria monocytogenes; listeria infections; drug delivery system; major histocompatibility antigen class 1; bacterial immunity; bacterial growth; gene replication; lymphocytic choriomeningitis virus; bacterial antigen; humans; human; choriomeningitis virus; listeriosis monocytogenes |
| Journal Title: | Current Opinion in Microbiology |
| Volume: | 7 |
| Issue: | 1 |
| ISSN: | 1369-5274 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2004-02-01 |
| Start Page: | 45 |
| End Page: | 50 |
| Language: | English |
| DOI: | 10.1016/j.mib.2003.12.002 |
| PROVIDER: | scopus |
| PUBMED: | 15036139 |
| DOI/URL: | |
| Notes: | Curr. Opin. Microbiol. -- Cited By (since 1996):65 -- Export Date: 16 June 2014 -- CODEN: COMIF -- Source: Scopus |
