Primary cutaneous B-cell lymphomas: Part I. Clinical features, diagnosis, and classification Journal Article


Authors: Suarez, A. L.; Pulitzer, M.; Horwitz, S.; Moskowitz, A.; Querfeld, C.; Myskowski, P. L.
Article Title: Primary cutaneous B-cell lymphomas: Part I. Clinical features, diagnosis, and classification
Abstract: Primary cutaneous B-cell lymphomas (PCBCLs) are defined as lymphomas with a B-cell phenotype that present in the skin without evidence of systemic or extracutaneous disease at initial presentation, after adequate staging. In non-Hodgkin lymphomas, the skin is the second most common site of extranodal involvement after the gastrointestinal tract. PCBCLs are histologically very similar to their nodal counterparts, and these histologic similarities can lead to confusion about both therapy and prognosis. This article will summarize the clinical, pathologic, and diagnostic features of the 3 main types of PCBCL: primary cutaneous follicle center lymphoma, primary cutaneous marginal zone lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg-type, and the appropriate evaluation and staging procedures for each of these entities. © 2013 by the American Academy of Dermatology, Inc.
Keywords: primary tumor; clinical feature; histopathology; staging; cancer diagnosis; b cell lymphoma; immunophenotyping; cancer classification; skin lymphoma; primary cutaneous b-cell lymphoma; primary cutaneous diffuse large b-cell lymphoma; primary cutaneous follicle center lymphoma; primary cutaneous marginal zone lymphoma; primary cutaneous b cell lymphoma; primary cutaneous diffuse large b cell lymphoma leg type
Journal Title: Journal of the American Academy of Dermatology
Volume: 69
Issue: 3
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2013-09-01
Start Page: 329.e1
End Page: 329.e11
Language: English
DOI: 10.1016/j.jaad.2013.06.012
PROVIDER: scopus
PUBMED: 23957984
DOI/URL:
Notes: --- - "Export Date: 1 October 2013" - "CODEN: JAADD" - "Source: Scopus"
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MSK Authors
  1. Melissa P Pulitzer
    203 Pulitzer
  2. Steven M Horwitz
    644 Horwitz
  3. Alison Moskowitz
    339 Moskowitz
  4. Patricia Myskowski
    216 Myskowski
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