Non-invasive skin imaging in cutaneous lymphomas Review
| Authors: | Taleb, E.; Yélamos, O.; Ardigo, M.; Christensen, R. E.; Geller, S. |
| Review Title: | Non-invasive skin imaging in cutaneous lymphomas |
| Abstract: | The diagnosis of cutaneous lymphomas is challenging and requires skin tissue for histology and immunophenotyping using immunohistochemistry and molecular studies. In recent years, the role of non-invasive imaging techniques has been described as part of the clinical assessment of cutaneous lymphoma lesions. Imaging modalities such as dermoscopy, reflectance confocal microscopy (RCM), and high frequency ultrasound (HFUS) have been shown to be very valuable in raising the clinical suspicion for lymphomas of the skin, and in distinguishing cutaneous lymphomas from inflammatory dermatoses such as lupus, psoriasis, or eczema. These non-invasive methods can be used to direct the clinician to the optimal biopsy site to maximize the histopathological results and minimize false negatives. These methods also have a potential place in monitoring treatment response. In this review we present a concise summary of the dermoscopic imaging, RCM, and HFUS features seen in cutaneous T-cell lymphomas (CTCL) and B-cell lymphomas (CBCL). © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG. |
| Keywords: | immunohistochemistry; human tissue; treatment response; histopathology; review; comparative study; cancer staging; t lymphocyte; dermoscopy; reflectance confocal microscopy; confocal microscopy; skin neoplasms; clinical assessment; pathology; diagnostic imaging; epiluminescence microscopy; inflammatory cell; false negative result; skin; cutaneous t cell lymphoma; skin tumor; echography; immunophenotyping; non invasive procedure; ultrasonography; stratum corneum; skin lymphoma; procedures; lymphoma, t-cell, cutaneous; disease burden; eczema; humans; human; evaluation study; high frequency ultrasound |
| Journal Title: | American Journal of Clinical Dermatology |
| Volume: | 25 |
| Issue: | 1 |
| ISSN: | 1175-0561 |
| Publisher: | Adis International Ltd |
| Date Published: | 2024-01-01 |
| Start Page: | 79 |
| End Page: | 89 |
| Language: | English |
| DOI: | 10.1007/s40257-023-00824-1 |
| PUBMED: | 37964050 |
| PROVIDER: | scopus |
| PMCID: | PMC10842086 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Shamir Geller -- Source: Scopus |
