Confocal reflectance microscopy in dermatology: Promise and reality of non-invasive diagnosis and monitoring Journal Article


Author: Gonzalez, S.
Article Title: Confocal reflectance microscopy in dermatology: Promise and reality of non-invasive diagnosis and monitoring
Abstract: In vivo reflectance confocal microscopy (RCM) constitutes a novel non-invasive imaging method that enables visualization of cells and structures in living skin in real time with resolution close to histological analysis. RCM has been successfully implemented in the assessment of benign and malignant lesions. It also enables monitoring dynamic changes in the skin over time and in response to different stimuli, such as ultraviolet exposure or specific treatments. The non-invasive nature of this technique allows repetitive sampling without biopsy collection, causing no further damage to the areas under investigation. In this article, I provide an overview of RCM, including the latest technological advances as well as novel applications in the characterization of both normal and pathological skin. © 2009 Academia Española de Dermatología y Venereología.
Keywords: squamous cell carcinoma; nonhuman; melanoma; reflectance confocal microscopy; actinic keratosis; basal cell carcinoma; confocal microscopy; skin biopsy; microscopy, confocal; skin neoplasms; malignant lentigo; skin cancer; histology; melanocytic nevus; seborrheic keratosis; amelanotic melanoma; dysplastic nevus; dermatofibroma; in vivo microscopy; non-invasive imaging techniques; dermatology; mycosis fungoides; non invasive measurement; paget nipple disease; skin diseases
Journal Title: Actas Dermo-Sifiliográficas
Volume: 100
Issue: Suppl. 2
ISSN: 0001-7310
Publisher: Elsevier España  
Date Published: 2009-12-01
Start Page: 59
End Page: 69
Language: English
DOI: 10.1016/s0001-7310(09)73380-0
PUBMED: 20096164
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 30 November 2010" - "CODEN: ADSIA" - "Source: Scopus"
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  1. Salvador Gonzalez Rodriguez
    203 Rodriguez