Primary cutaneous B-cell lymphomas Journal Article


Authors: Rozati, S.; Dummer, R.; Lunning, M. A.; Horwitz, S.; Ott, G.; Hsi, E. D.
Article Title: Primary cutaneous B-cell lymphomas
Abstract: Cutaneous lymphomas (CL) are a heterogeneous group of neoplasias that are characterized by an accumulation of mononuclear, mostly lymphocytic cells in the skin (Burg et al, J Dtsch Dermatol Ges 4:914-933, 2006). Cutaneous lymphomas are the second most prevalent extranodal non-Hodgkin lymphomas (after gastrointestinal), representing approximately 19 % of extranodal non-Hodgkin lymphomas. Primary cutaneous B-cell lymphomas represent less than one third of cutaneous lymphomas (Willemze et al, Blood 105:3768-3785, 2005; Bradford et al, Blood 113:5064-5073, 2009). Distinguishing between low-grade CBCL and reactive B-cell pseudolymphomas can be quite difficult; even clonality studies cannot with certainty separate the two entities (Dummer et al, Ann Oncol 19(Suppl 2):ii72-ii76, 2008). The World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) has categorized primary cutaneous B-cell lymphomas to three main subtypes: primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous marginal zone lymphoma(PCMZL), and primary cutaneous diffuse large B-cell lymphoma (DLBCL) ("leg type” and "others”) (Willemze et al, Blood 105:3768-3785, 2005). © Springer-Verlag Berlin Heidelberg 2014.
Journal Title: Hematologic Malignancies
ISSN: 2197-9766
Publisher: Springer  
Date Published: 2014-01-01
Start Page: 353
End Page: 364
Language: English
DOI: 10.1007/978-3-642-39590-1_19
PROVIDER: scopus
DOI/URL:
Notes: Chapter 19 in "Rare Lymphomas" (ISBN: 978-3-642-39589-5) -- Export Date: 2 November 2017 -- Source: Scopus
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  1. Steven M Horwitz
    645 Horwitz