Update in HIV lymphoma Journal Article
| Author: | Noy, A. |
| Article Title: | Update in HIV lymphoma |
| Abstract: | PURPOSE OF REVIEW: Despite the control of HIV infection in industrialized nations, individuals infected with HIV remain at increased risk of malignancies. Lymphoma is the most common HIV-associated malignancy in these countries. This review summarizes progress from January 2005 to March 2006. RECENT FINDINGS: Investigators continue to demonstrate that HIV-associated non-Hodgkin's lymphoma remains a significant problem, even in the era of highly active antiretroviral therapy. The majority of work has been in diffuse large B-cell lymphoma, with infusional therapy remaining promising, and rituximab an area of investigation. The latter improves complete response rates, but is associated with an increased incidence of infections. Biological insights have been gained into the spectrum of HIV-associated non-Hodgkin's lymphoma and Hodgkin's disease, and include further work on virological co-infections. SUMMARY: The outcome for individuals infected with HIV and developing non-Hodgkin's lymphoma and Hodgkin's disease continues to improve as insights into the pathophysiology and treatment advance. © 2006 Lippincott Williams & Wilkins. |
| Keywords: | prednisone; clinical trial; review; doxorubicin; cancer combination chemotherapy; drug efficacy; nonhuman; rituximab; drug megadose; human immunodeficiency virus infection; antineoplastic agent; imatinib; disease association; interleukin 2; etoposide; antineoplastic combined chemotherapy protocols; cyclophosphamide; dexamethasone; melphalan; vincristine; drug effect; dose-response relationship, drug; carmustine; hodgkin disease; vincristine sulfate; b cell lymphoma; nonhodgkin lymphoma; non-hodgkin's lymphoma; drug response; comorbidity; daunorubicin; drug infusion; bleomycin; vindesine; virus infection; large cell lymphoma; antiretrovirus agent; highly active antiretroviral therapy; antiretroviral therapy, highly active; high risk population; lymphoma, aids-related; ganciclovir; burkitt lymphoma; hiv; zidovudine; anti-retroviral agents; thallium; primary effusion lymphoma; mucosa associated lymphoid tissue lymphoma; hodgkin's disease; industrialization |
| Journal Title: | Current Opinion in Oncology |
| Volume: | 18 |
| Issue: | 5 |
| ISSN: | 1040-8746 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2006-09-01 |
| Start Page: | 449 |
| End Page: | 455 |
| Language: | English |
| DOI: | 10.1097/01.cco.0000239883.23839.ac |
| PUBMED: | 16894292 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 14" - "Export Date: 4 June 2012" - "CODEN: CUOOE" - "Source: Scopus" |
