Update on HIV lymphoma Journal Article
| Author: | Noy, A. |
| Article Title: | Update on HIV lymphoma |
| Abstract: | In industrialized nations people infected with HIV remain at increased risk for malignancies despite highly active antiretroviral therapy. In these countries, lymphoma is the most common HIV-associated malignancy. This review summarizes progress from January 2005 to February 2007. The majority of investigation has been in diffuse large B cell lymphoma, with infusional therapy remaining promising but cumbersome. Rituximab likely improves complete response rates, and, possibly overall survival, but is likely associated with increased infections in a subset of patients with very low CD4 counts. Biologic insights have been attained in the spectrum of HIV-associated non-Hodgkin's lymphoma, Hodgkin's lymphoma, and virologic coinfections, Overall, the outcome for non-Hodgkin's lymphoma and Hodgkin's lymphoma in the setting of HIV continues to improve as insights into the pathophysiology and treatment advance. Copyright © 2007 by Current Medicine Group LLC. |
| Keywords: | cancer survival; protein expression; treatment outcome; antibiotic agent; prednisone; clinical trial; review; doxorubicin; cancer combination chemotherapy; cancer risk; drug efficacy; unspecified side effect; clinical trials as topic; primary central nervous system lymphoma; cytarabine; methotrexate; rituximab; drug megadose; human immunodeficiency virus infection; cancer incidence; diagnostic accuracy; interleukin 2; cancer prevention; low drug dose; infection; etoposide; antineoplastic combined chemotherapy protocols; interleukin 10; cyclophosphamide; vincristine; autologous stem cell transplantation; ifosfamide; high risk patient; hodgkin disease; b lymphocyte; drug fatality; vincristine sulfate; b cell lymphoma; cd20 antigen; granzyme b; papilledema; nonhodgkin lymphoma; drug response; lymphoma; bleomycin; sepsis; vindesine; immunophenotyping; seizure; large cell lymphoma; antiretrovirus agent; cd4 lymphocyte count; highly active antiretroviral therapy; encephalitis; hermes antigen; neurologic disease; granulocyte colony stimulating factor; lymphoma, aids-related; ganciclovir; burkitt lymphoma; opportunistic infection; zidovudine; virus carcinogenesis; common acute lymphoblastic leukemia antigen; syndecan 1; anti-retroviral agents; thallium; primary effusion lymphoma; mucosa associated lymphoid tissue lymphoma; brain scintiscanning; cauda equina syndrome |
| Journal Title: | Current Oncology Reports |
| Volume: | 9 |
| Issue: | 5 |
| ISSN: | 1523-3790 |
| Publisher: | Springer |
| Date Published: | 2007-09-01 |
| Start Page: | 384 |
| End Page: | 390 |
| Language: | English |
| DOI: | 10.1007/s11912-007-0052-x |
| PUBMED: | 17706167 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: CORUA" - "Source: Scopus" |
