Update in HIV-associated lymphoma Journal Article
| Author: | Noy, A. |
| Article Title: | Update in HIV-associated lymphoma |
| Abstract: | Purpose of review: Infection with human immunodeficiency virus (HIV) is associated with an increased risk of non-Hodgkin lymphoma and Hodgkin disease. This review summarizes developments within the past 18 months. Recent findings: Investigators continue to demonstrate that many standard therapies similar to those used in the non-HIV- infected population may be used in the HAART era for patients infected with HIV. Biologic differences do exist, however, and not all treatments and outcomes are directly translatable. Some treatments, such as rituximab in combination with CHOP, may have unforeseen toxicity. Nonetheless, high-dose therapy does appear feasible and may offer curative therapy for those with refractory and relapsed disease. Summary: HIV-infected persons appear to benefit from most, but not all standard treatments for lymphoma. © 2004 Lippincott Williams & Wilkins. |
| Keywords: | protein expression; prednisone; review; doxorubicin; drug efficacy; cytarabine; methotrexate; rituximab; drug megadose; human immunodeficiency virus infection; protein analysis; disease association; protein bcl 2; anemia; etoposide; thrombocytopenia; interleukin 10; cyclophosphamide; vincristine; protein p53; ifosfamide; hodgkin disease; central nervous system; drug fatality; b cell lymphoma; nonhodgkin lymphoma; lymphoma; human immunodeficiency virus; large cell lymphoma; antiretrovirus agent; highly active antiretroviral therapy; virus replication; drug dose regimen; lymphoma, aids-related; burkitt lymphoma; hiv; non-hodgkin lymphoma; cell adhesion molecule; common acute lymphoblastic leukemia antigen; plasmablastic lymphoma; humans; human; priority journal |
| Journal Title: | Current Opinion in Oncology |
| Volume: | 16 |
| Issue: | 5 |
| ISSN: | 1040-8746 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2004-09-01 |
| Start Page: | 450 |
| End Page: | 454 |
| Language: | English |
| DOI: | 10.1097/00001622-200409000-00007 |
| PROVIDER: | scopus |
| PUBMED: | 15314514 |
| DOI/URL: | |
| Notes: | Curr. Opin. Oncol. -- Cited By (since 1996):9 -- Export Date: 16 June 2014 -- CODEN: CUOOE -- Source: Scopus |
