Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: A meta-regression Journal Article


Authors: Malik, A.; Jairam, M. P.; Chow, R.; Mirshahvalad, S. A.; Veit-Haibach, P.; Simone, C. B. 2nd
Article Title: Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: A meta-regression
Abstract: Aim: The aim of this meta-regression was to assess the impact of mean/median age, mean/median tumor size, percentage of males in total sample, and total sample size on the comparative effectiveness of radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT). Methods: Ten studies reporting on the composite outcome of overall survival and local control were included. Results: A significant relationship was found between age and overall survival at 1 and 2 for both RFA and SBRT. A significant relationship was noted also between age and local control at 1 and 2 years for RFA. Conclusion: Patients treated with SBRT had a wider range of tumor sizes and larger tumor sizes; no relationship was observed between tumor size and overall survival or local control by SBRT.
Keywords: survival; hepatocellular carcinoma; radiotherapy; local control; stereotactic body radiation therapy; outcomes; radiofrequency; ablation; meta-regression
Journal Title: Future Oncology
Volume: 19
Issue: 4
ISSN: 1479-6694
Publisher: Future Medicine  
Date Published: 2023-02-01
Start Page: 279
End Page: 287
Language: English
ACCESSION: WOS:000949735100001
DOI: 10.2217/fon-2022-0893
PROVIDER: wos
PMCID: PMC10135443
PUBMED: 36916490
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Charles B Simone -- Source: Wos
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Charles Brian Simone
    193 Simone
  2. Ronald Chow
    13 Chow