Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: A meta-regression Journal Article
| Authors: | Malik, A.; Jairam, M. P.; Chow, R.; Mirshahvalad, S. A.; Veit-Haibach, P.; Simone, C. B. 2nd |
| Article Title: | Radiofrequency ablation versus stereotactic body radiation therapy for hepatocellular carcinoma: A meta-regression |
| Abstract: | Aim: The aim of this meta-regression was to assess the impact of mean/median age, mean/median tumor size, percentage of males in total sample, and total sample size on the comparative effectiveness of radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT). Methods: Ten studies reporting on the composite outcome of overall survival and local control were included. Results: A significant relationship was found between age and overall survival at 1 and 2 for both RFA and SBRT. A significant relationship was noted also between age and local control at 1 and 2 years for RFA. Conclusion: Patients treated with SBRT had a wider range of tumor sizes and larger tumor sizes; no relationship was observed between tumor size and overall survival or local control by SBRT. |
| Keywords: | survival; hepatocellular carcinoma; radiotherapy; local control; stereotactic body radiation therapy; outcomes; radiofrequency; ablation; meta-regression |
| Journal Title: | Future Oncology |
| Volume: | 19 |
| Issue: | 4 |
| ISSN: | 1479-6694 |
| Publisher: | Future Medicine |
| Date Published: | 2023-02-01 |
| Start Page: | 279 |
| End Page: | 287 |
| Language: | English |
| ACCESSION: | WOS:000949735100001 |
| DOI: | 10.2217/fon-2022-0893 |
| PROVIDER: | wos |
| PMCID: | PMC10135443 |
| PUBMED: | 36916490 |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Charles B Simone -- Source: Wos |
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