Assist control versus synchronized intermittent mandatory ventilation during acute respiratory failure Journal Article


Authors: Groeger, J. S.; Levinson, M. R.; Carlon, G. C.
Article Title: Assist control versus synchronized intermittent mandatory ventilation during acute respiratory failure
Abstract: Controversy persists as to the relative advantages and disadvantages of synchronized intermittent mandatory ventilation (SIMV) vs. assist/control ventilation (A/C) in the management of acute respiratory failure. In an effort to resolve these differences, we evaluated differences in hemodynamic, metabolic, ventilatory, and oxygenation variables during ventilation with both SIMV and A/C using a crossover protocol in critically ill patients without chronic obstructive pulmonary disease. Despite differences in ventilation, resting energy expenditure, and oxygen delivery in specific subgroups of patients, we found no evidence to support any clear-cut advantage of SIMV or A/C in the acute management of respiratory failure. Careful assessment of individual patients may indicate which patient might benefit from each modality of support.
Keywords: adult; clinical article; controlled study; clinical trial; methodology; hemodynamic monitoring; oxygenation; artificial ventilation; acute respiratory failure; human; priority journal; intermittent mandatory ventilation
Journal Title: Critical Care Medicine
Volume: 17
Issue: 7
ISSN: 0090-3493
Publisher: Lippincott Williams & Wilkins  
Date Published: 1989-07-01
Start Page: 607
End Page: 612
Language: English
DOI: 10.1097/00003246-198907000-00002
PUBMED: 2736919
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
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  1. Jeffrey Groeger
    91 Groeger
  2. Graziano   Carlon
    50 Carlon