The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein Journal Article
| Authors: | Stamnes, M. A.; Rothman, J. E. |
| Article Title: | The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein |
| Abstract: | The small GTP-binding protein, ADP-ribosylation factor (ARF), has previously been shown to mediate the binding to Golgi membranes of the coatomer of nonclathrin-coated (COP-coated) vesicles. We now report that ARF is also required for the binding of the AP-1 adaptor protein of clathrin-coated vesicles to Golgi membranes. The binding of coat proteins from both clathrin- and COP-coated vesicles requires an additional Golgi membrane-associated factor. These results suggest that a mechanistic similarity underlies diverse types of vesicle coats. © 1993. |
| Keywords: | controlled study; nonhuman; proteins; animal; cell protein; protein binding; gtp-binding proteins; liver; brain; cattle; rats; adenosine triphosphate; guanosine triphosphate; guanine nucleotide binding protein; cytosol; in vitro; membrane binding; golgi complex; adenosine diphosphate ribosylation factor; membrane vesicle; clathrin; intracellular membranes; golgi apparatus; coat protein; bos taurus; adp-ribosylation factors; guanosine 5' o (3 thiotriphosphate); priority journal; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; adaptor protein complex alpha subunits; coated pits, cell-membrane; adaptor protein complex gamma subunits; adaptor proteins |
| Journal Title: | Cell |
| Volume: | 73 |
| Issue: | 5 |
| ISSN: | 0092-8674 |
| Publisher: | Cell Press |
| Date Published: | 1993-06-04 |
| Start Page: | 999 |
| End Page: | 1005 |
| Language: | English |
| DOI: | 10.1016/0092-8674(93)90277-w |
| PUBMED: | 8500185 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
