Trends in the susceptibility of tuberculosis in New York City, 1987-1991 Journal Article
| Authors: | Sepkowitz, K. A.; Telzak, E. E.; Recalde, S.; Armstrong, D.; New York City Area Tuberculosis Working Group |
| Article Title: | Trends in the susceptibility of tuberculosis in New York City, 1987-1991 |
| Abstract: | The annual number of cases of tuberculosis in New York City has increased since 1978. In addition, in 1991 a 1-month survey of cases of tuberculosis in New York City found that 33% of all cases were resistant to at least one drug. To determine susceptibility trends from 1987 to 1991, a period during which an unprecedented rise in resistant tuberculosis occurred in New York City, we reviewed the microbiology records of 44 New York City hospitals (comprising >; 14, 000 cases). The percentage of cases resistant to at least one drug rose from 19% in 1987 to 28% in 1991, and the percentage of cases resistant to isoniazid rose from 13% in 1987 to 23% in 1991, while resistance to at least both isoniazid and rifampin rose from 6% to 14%. The rise of multidrug-resistant tuberculosis occurred in all four surveyed boroughs (counties) of New York City. These data demonstrate how rapidly multidrug-resistant tuberculosis can appear, and they suggest that initial empirical regimens should be broadened at certain hospitals. © 1994 by The University of Chicago. |
| Keywords: | retrospective studies; major clinical study; united states; comparative study; human immunodeficiency virus infection; incidence; drug resistance; risk factor; time factors; mycobacterium tuberculosis; patient compliance; bias (epidemiology); disease predisposition; rifampicin; infection risk; multidrug resistance; tuberculosis; streptomycin; antitubercular agents; lung tuberculosis; drug resistance, microbial; ethambutol; isoniazid; human; priority journal; article; tuberculosis, multidrug-resistant |
| Journal Title: | Clinical Infectious Diseases |
| Volume: | 18 |
| Issue: | 5 |
| ISSN: | 1058-4838 |
| Publisher: | Oxford University Press |
| Date Published: | 1994-05-01 |
| Start Page: | 755 |
| End Page: | 759 |
| Language: | English |
| DOI: | 10.1093/clinids/18.5.755 |
| PROVIDER: | scopus |
| PUBMED: | 8075265 |
| DOI/URL: | |
| Notes: | Export Date: 14 January 2019 -- Article -- Source: Scopus |
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