Tuberculosis among foreign-born persons in New York City, 1992-1994: Implications for tuberculosis control Journal Article

Authors: Tornieporth, N. G.; Ptachewich, Y.; Poltoratskaia, N.; Ravi, B. S.; Katapadi, M.; Berger, J. J.; Dahdouh, M.; Segal-Maurer, S.; Glatt, A.; Adamis, R.; Lerner, C.; Armstrong, D.; Weiner, M.; D'Amato, R.; Kiehn, T.; Lavie, S.; Stoeckle, M. Y.; Riley, L. W.
Article Title: Tuberculosis among foreign-born persons in New York City, 1992-1994: Implications for tuberculosis control
Abstract: OBJECTIVE: To study the pattern of transmission of tuberculosis (TB) among foreign-born persons living in New York City. DESIGN: A retrospective multicenter study comparing 158 foreign-born patients to 231 US-born patients diagnosed with TB between 1992 and 1994. The patients were stratified according to their Mycobacterium tuberculosis isolate DNA fingerprint patterns. RESULTS: Nineteen (16%) of 122 isolates from foreign-born TB patients and 75 (42%) of 180 isolates from US-born TB patients had DNA fingerprint patterns (cluster patterns) indicative of recent exogenous transmission (P < 0.001). All cluster pattern strains from foreign-born cases were identical to those found among US-born pa- tients. The likelihood of infection with a cluster pattern strain among foreign-born persons increased with duration of residence in the US, and was significantly associated with being homeless (P < 0.05), or having multidrug-resistant TB (P = 0.00072). CONCLUSION: Although most (84%) cases of TB among foreign-born persons in New York City appear to result from reactivation of infections they acquired abroad, the ones who acquire new infections become infected with strains that are already circulating among the US-born TB patients in New York City, and they have risk factors similar to those faced by US-born tuberculosis patients.
Keywords: adult; middle aged; retrospective studies; genetics; clinical trial; united states; cluster analysis; statistics; retrospective study; mycobacterium tuberculosis; multicenter study; new york city; dna fingerprinting; microbiology; migration; tuberculosis; disease transmission; ethnology; lung tuberculosis; immigration; emigration and immigration; tuberculosis, pulmonary; humans; human; male; female; article
Journal Title: International Journal of Tuberculosis and Lung Disease
Volume: 1
Issue: 6
ISSN: 1027-3719
Publisher: International Union against Tuberculosis and Lung Disease  
Date Published: 1997-12-01
Start Page: 528
End Page: 535
Language: English
PUBMED: 9487451
PROVIDER: scopus
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
Citation Impact
MSK Authors
  1. Timothy E Kiehn
    95 Kiehn
  2. Donald Armstrong
    229 Armstrong