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Tyler R Simpson

Formats
  1. Journal Article (6)
  2. Meeting Abstract (1)
Groups
  1. Department of Medicine (3)
  2. GSK Faculty (2)
  3. Melanoma and Immunotherapeutics Service (2)
  4. Sloan Kettering Institute Faculty (2)
  5. Solid Tumor Oncology Division (2)
  6. Division of Subspecialty Medicine (1)

More Groups

People
  1. James Allison (5)
  2. Sergio Quezada (5)
  3. Karl Peggs (2)
  4. Amariliz Rivera-Medina (1)
  5. Derek Sant'angelo (1)
  6. Eric Pamer (1)

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Years
  1. 2013 (1)
  2. 2011 (1)
  3. 2010 (2)
  4. 2008 (1)
  5. 2007 (1)
  6. 2006 (1)
Publications
  1. Journal of Experimental Medicine (3)
  2. Blood (1)
  3. Current Opinion in Immunology (1)
  4. Immunity (1)
  5. Immunological Reviews (1)
Publishers
  1. Rockefeller University Press (3)
  2. American Society of Hematology (1)
  3. Cell Press (1)
  4. Elsevier Inc. (1)
  5. Wiley Blackwell (1)

Results (7)

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  • Fc-dependent depletion of tumor-infiltrating regulatory t cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma
    Journal Article

    Simpson, T. R.; Li, F.; Montalvo Ortiz, W.; Sepulveda, M. A.; Bergerhoff, K.; Arce, F.; Roddie, C.; Henry, J. Y.; Yagita, H.; Wolchok, J. D.; more...
    Journal of Experimental Medicine (2013)

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  • Shifting the equilibrium in cancer immunoediting: From tumor tolerance to eradication
    Journal Article

    Quezada, S. A.; Peggs, K. S.; Simpson, T. R.; Allison, J. P.
    Immunological Reviews (2011)

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  • Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)
    Journal Article

    Simpson, T. R.; Quezada, S. A.; Allison, J. P.
    Current Opinion in Immunology (2010)

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  • Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
    Journal Article

    Quezada, S. A.; Simpson, T. R.; Peggs, K. S.; Merghoub, T.; Vider, J.; Fan, X.; Blasberg, R.; Yagita, H.; Muranski, P.; Antony, P. A.; more...
    Journal of Experimental Medicine (2010)

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  • Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
    Journal Article

    Quezada, S. A.; Peggs, K. S.; Simpson, T. R.; Shen, Y.; Littman, D. R.; Allison, J. P.
    Journal of Experimental Medicine (2008)

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  • Dissociation of systemic and local anti-tumor immunity following depletion of regulatory T cells limits therapeutic activity in established tumors
    Meeting Abstract

    Peggs, K. S.; Quezada, S. A.; Simpson, T. R.; Allison, J. P.
    Blood (2007)

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  • Innate immune activation and CD4+ T cell priming during respiratory fungal infection
    Journal Article

    Rivera, A.; Ro, G.; Van Epps, H. L.; Simpson, T.; Leiner, I.; Sant'angelo, D. B.; Pamer, E. G.
    Immunity (2006)

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