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Derek S Tan

Formats
  1. Journal Article (75)
  2. Meeting Abstract (12)
  3. Book Section (1)
  4. Editorial (1)
  5. Research Letter (1)
  6. Review (1)
Groups
  1. Center for Molecular Imaging and Biotechnology (CMIB) (91)
  2. GSK Faculty (91)
  3. Molecular Pharmacology and Chemistry Program Faculty (91)
  4. Sloan Kettering Institute Faculty (91)
  5. Sloan Kettering Institute Postdocs (22)
  6. MSK Grad Students (18)

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People
  1. David Gin (10)
  2. David Scheinberg (7)
  3. Xuequan Lu (7)
  4. Alberto Fernandez-Tejada (6)
  5. Cheng Ji (6)
  6. Thomas Gardner (6)

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Years
  1. 2024 (5)
  2. 2023 (5)
  3. 2022 (3)
  4. 2021 (1)
  5. 2020 (4)
  6. 2019 (7)

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Publications
  1. Organic Letters (10)
  2. Abstracts of Papers of the American Chemical Society (6)
  3. Journal of the American Chemical Society (6)
  4. Nature Chemical Biology (6)
  5. Bioorganic & Medicinal Chemistry Letters (5)
  6. Chemical Science (4)

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Publishers
  1. American Chemical Society (32)
  2. Nature Publishing Group (17)
  3. Royal Society of Chemistry (10)
  4. Pergamon-Elsevier Science Ltd (8)
  5. Elsevier Inc. (4)
  6. American Society for Microbiology (3)

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Results (91)

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  • Active site remodelling accompanies thioester bond formation in the SUMO E1
    Journal Article

    Olsen, S. K.; Capili, A. D.; Lu, X.; Tan, D. S.; Lima, C. D.
    Nature (2010)

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  • Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes
    Journal Article

    Lu, X.; Olsen, S. K.; Capili, A. D.; Cisar, J. S.; Lima, C. D.; Tan, D. S.
    Journal of the American Chemical Society (2010)

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  • Expanding the range of 'druggable' targets with natural product-based libraries: an academic perspective
    Journal Article

    Bauer, R. A.; Wurst, J. M.; Tan, D. S.
    Current Opinion in Chemical Biology (2010)

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  • The tert-Butylsulfinamide lynchpin in transition-metal-mediated multiscaffold library synthesis
    Journal Article

    Bauer, R. A.; Diblasi, C. M.; Tan, D. S.
    Organic Letters (2010)

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  • Stereoselective synthesis of benzannulated spiroketals: Influence of the aromatic ring on reactivity and conformation
    Journal Article

    Liu, G.; Wurst, J. M.; Tan, D. S.
    Organic Letters (2009)

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  • Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis
    Journal Article

    Lu, X.; Zhang, H.; Tonge, P. J.; Tan, D. S.
    Bioorganic & Medicinal Chemistry Letters (2008)

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  • Mycobacterial phenolic glycolipid virulence factor biosynthesis: Mechanism and small-molecule inhibition of polyketide chain initiation
    Journal Article

    Ferreras, J. A.; Stirrett, K. L.; Lu, X.; Ryu, J. S.; Soll, C. E.; Tan, D. S.; Quadri, LuisE N.
    Chemistry and Biology (2008)

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  • Small molecule inhibition of microbial natural product biosynthesis - An emerging antibiotic strategy
    Journal Article

    Cisar, J. S.; Tan, D. S.
    Chemical Society Reviews (2008)

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  • Diversity-oriented synthesis
    Book Section

    Tan, D. S.
    In Schreiber, S. L.; Kapoor, T. M.; Wess, G. (Eds.) Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Volume 1-3 (2007)

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  • Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
    Meeting Abstract

    Ferreras, J. A.; Ryu, J. S.; Di Lello, F.; Cisar, J. S.; Wu, N.; Tan, D. S.; Quadri, L. E. N.
    Drugs of the Future (2007)

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