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Friederike Pastore

Formats
  1. Journal Article (6)
  2. Meeting Abstract (6)
Groups
  1. Adult Leukemia (12)
  2. Center for Hematologic Malignancies (12)
  3. Center for Molecular Imaging and Biotechnology (CMIB) (12)
  4. Department of Medicine (12)
  5. Executive Committee, Center for Hematologic Malignancies (12)
  6. GSK Faculty (12)

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People
  1. Ross Levine (12)
  2. Wenbin Xiao (6)
  3. Maria Arcila (5)
  4. Raajit Rampal (5)
  5. Mikhail Roshal (4)
  6. Richard Koche (4)

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Years
  1. 2020 (2)
  2. 2019 (1)
  3. 2018 (4)
  4. 2017 (1)
  5. 2016 (2)
  6. 2015 (2)
Publications
  1. Blood (3)
  2. Haematologica (2)
  3. Blood Advances (1)
  4. Cancer Discovery (1)
  5. Cancer Research (1)
  6. JAMA - Journal of the American Medical Association (1)

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Publishers
  1. American Society of Hematology (4)
  2. American Association for Cancer Research (2)
  3. Ferrata Storti Foundation (2)
  4. Amer Soc Clinical Investigation Inc (1)
  5. American Medical Association (1)
  6. Nature Publishing Group (1)

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Results (12)

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  • Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity in in vitro and in vivo models
    Meeting Abstract

    Bhagwat, N.; Zhang, Y.; Lin, H.; Wang, M.; Rominger, D.; Emm, T.; Chugani-Mahtani, D.; Angelis, D.; Shetty, R.; Leal, R.; more...
    Cancer Research (2020)

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  • PRMT5 inhibition modulates E2F1 methylation and gene-regulatory networks leading to therapeutic efficacy in JAK2(V617F)-mutant MPN
    Journal Article

    Pastore, F.; Bhagwat, N.; Pastore, A.; Radzisheuskaya, A.; Karzai, A.; Krishnan, A.; Li, B.; Bowman, R. L.; Xiao, W.; Viny, A. D.; more...
    Cancer Discovery (2020)

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  • PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2VF mutant MPN
    Meeting Abstract

    Pastore, F.; Bhagwat, N.; Krishnan, A.; Pastore, A.; Li, B.; Bowman, R. L.; Xiao, W.; Viny, A. D.; Karzai, A.; Zouak, A.; more...
    Blood (2019)

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  • PHF6 mutations are mutually exclusive to TP53 mutations, and define a distinct subgroup of secondary acute myeloid leukemia associated with a primitive stem/progenitor immunophenotype, absent complex karyotype and relatively better outcomes
    Meeting Abstract

    Xiao, W.; Goldberg, A. D.; Ball, B.; Famulare, C.; Pastore, F.; Tallman, M. S.; Zhang, Y.; Arcila, M. E.; Papaemmanuil, E.; Levine, R. L.; more...
    Blood (2018)

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  • Targeting the CALR interactome in myeloproliferative neoplasms
    Journal Article

    Pronier, E.; Cifani, P.; Merlinsky, T. R.; Berman, K. B.; Somasundara, A. V. H.; Rampal, R. K.; LaCava, J.; Wei, K. E.; Pastore, F.; Maag, J. L. V.; more...
    JCI Insight (2018)

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  • PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation
    Journal Article

    Xiao, W.; Bharadwaj, M.; Levine, M.; Farnhoud, N.; Pastore, F.; Getta, B. M.; Hultquist, A.; Famulare, C.; Medina, J. S.; Patel, M. A.; more...
    Blood Advances (2018)

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  • PHF6 mutations define a subgroup of mixed phenotype acute leukemia with aberrant T-cell differentiation
    Meeting Abstract

    Lewis, N.; Pastore, F.; Kumar, P.; Getta, B.; Hultquist, A.; Shaffer, B.; Giralt, S.; Rampal, R.; Arcila, M.; Levine, R.; more...
    Modern Pathology (2018)

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  • PHF6 mutations defines a subgroup of mixed phenotype of acute leukemia with aberrant T-cell differentiation
    Meeting Abstract

    Xiao, W.; Pastore, F.; Getta, B.; Hultquist, A.; Shaffer, B. C.; Giralt, S. A.; Rampal, R. K.; Arcila, M. E.; Levine, R. L.; Roshal, M.
    Blood (2017)

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  • DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling
    Journal Article

    Guryanova, O. A.; Shank, K.; Spitzer, B.; Luciani, L.; Koche, R. P.; Garrett-Bakelman, F. E.; Ganzel, C.; Durham, B. H.; Mohanty, A.; Hoermann, G.; more...
    Nature Medicine (2016)

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  • Epigenetic regulators and their impact on therapy in acute myeloid leukemia
    Journal Article

    Pastore, F.; Levine, R. L.
    Haematologica (2016)

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