Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity in in vitro and in vivo models Meeting Abstract
| Authors: | Bhagwat, N.; Zhang, Y.; Lin, H.; Wang, M.; Rominger, D.; Emm, T.; Chugani-Mahtani, D.; Angelis, D.; Shetty, R.; Leal, R.; Gowen-MacDonald, W.; Grego, A.; Luengo, J.; Manshouri, T.; Pastore, F.; Levine, R. L.; Verstovsek, S.; Ruggeri, B.; Scherle, P.; Vaddi, K. |
| Abstract Title: | Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity in in vitro and in vivo models |
| Meeting Title: | 111th Annual Meeting of the American Association for Cancer Research (AACR) |
| Journal Title: | Cancer Research |
| Volume: | 80 |
| Issue: | 16 Suppl. |
| Meeting Dates: | 2020 Apr 27-28/Jun 22-24 |
| Meeting Location: | Philadelphia, PA |
| ISSN: | 0008-5472 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 2020-08-01 |
| Language: | English |
| ACCESSION: | WOS:000590059304480 |
| DOI: | 10.1158/1538-7445.Am2020-2915 |
| PROVIDER: | wos |
| Notes: | Meeting Abstract: 2915 -- Due to COVID-19 pandemic, the conference was held virtually -- Source: Wos |
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