PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2VF mutant MPN Meeting Abstract


Authors: Pastore, F.; Bhagwat, N.; Krishnan, A.; Pastore, A.; Li, B.; Bowman, R. L.; Xiao, W.; Viny, A. D.; Karzai, A.; Zouak, A.; Park, Y. C.; Cordner, K.; Braunstein, S.; Grego, A.; Mehta, J.; Durham, B. H.; Koche, R. P.; Maag, J.; Scherle, P.; Vaddi, K.; Levine, R. L.
Abstract Title: PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2VF mutant MPN
Meeting Title: 61st Annual Meeting and Exposition of the American Society of Hematology (ASH)
Journal Title: Blood
Volume: 134
Issue: Suppl. 1
Meeting Dates: 2019 Dec 7-10
Meeting Location: Orlando, FL
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2019-11-13
Language: English
ACCESSION: WOS:000518218500668
DOI: 10.1182/blood-2019-127122
PROVIDER: wos
Notes: Meeting Abstract: 473 -- Source: Wos
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MSK Authors
  1. Ross Levine
    776 Levine
  2. Robert L Bowman
    52 Bowman
  3. Richard Patrick Koche
    174 Koche
  4. Aaron David Viny
    50 Viny
  5. Benjamin Heath Durham
    115 Durham
  6. Friederike   Pastore
    12 Pastore
  7. Alessandro   Pastore
    55 Pastore
  8. Wenbin Xiao
    108 Xiao
  9. Jesper Lars Viktor Maag
    14 Maaaag
  10. Bing Li
    8 Li
  11. Anouar Zouak
    4 Zouak
  12. Abdul Karzai
    8 Karzai
  13. Young Park
    16 Park