BrachyView, a novel in-body imaging system for HDR prostate brachytherapy: Experimental evaluation Journal Article


Authors: Safavi-Naeini, M.; Han, Z.; Alnaghy, S.; Cutajar, D.; Petasecca, M.; Lerch, M. L. F.; Franklin, D. R.; Bucci, J.; Carrara, M.; Zaider, M.; Rosenfeld, A. B.
Article Title: BrachyView, a novel in-body imaging system for HDR prostate brachytherapy: Experimental evaluation
Abstract: Purpose: This paper presents initial experimental results from a prototype of high dose rate (HDR) BrachyView, a novel in-body source tracking system for HDR brachytherapy based on a multipinhole tungsten collimator and a high resolution pixellated silicon detector array. The probe and its associated position estimation algorithms are validated and a comprehensive evaluation of the accuracy of its position estimation capabilities is presented. Methods: The HDR brachytherapy source is moved through a sequence of positions in a prostate phantom, for various displacements in x, y, and z. For each position, multiple image acquisitions are performed, and source positions are reconstructed. Error estimates in each dimension are calculated at each source position and combined to calculate overall positioning errors. Gafchromic film is used to validate the accuracy of source placement within the phantom. Results: More than 90% of evaluated source positions were estimated with an error of less than one millimeter, with the worst-case error being 1.3 mm. Experimental results were in close agreement with previously published Monte Carlo simulation results. Conclusions: The prototype of HDR BrachyView demonstrates a satisfactory level of accuracy in its source position estimation, and additional improvements are achievable with further refinement of HDR BrachyView's image processing algorithms. © 2015 American Association of Physicists in Medicine.
Keywords: brachytherapy; hdr; brachyview; in vivo dosimetry
Journal Title: Medical Physics
Volume: 42
Issue: 12
ISSN: 0094-2405
Publisher: American Association of Physicists in Medicine  
Date Published: 2015-12-01
Start Page: 7098
End Page: 7107
Language: English
DOI: 10.1118/1.4935866
PROVIDER: scopus
PUBMED: 26632063
DOI/URL:
Notes: Article -- Export Date: 1 July 2016 -- Source: Scopus
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  1. Marco Zaider
    171 Zaider