BrachyView: Feasibility study into the application of Timepix detectors for soft tissue thickness imaging in prostate brachytherapy treatment Journal Article


Authors: Loo, K. J.; Jakubek, J.; Zemlicka, J.; Petasecca, M.; Safavi-Naeini, M.; Bucci, J.; Zaider, M.; Rosenfeld, A. B.
Article Title: BrachyView: Feasibility study into the application of Timepix detectors for soft tissue thickness imaging in prostate brachytherapy treatment
Abstract: BrachyView is a novel in-body imaging system for real-time intraoperative prostate brachytherapy treatment planning, which monitors the position of low dose rate brachytherapy seeds using an array of high-resolution pixelated silicon detectors (Timepix). The detector array is also capable of performing in-body imaging of the prostate when used in conjunction with an external X-ray source. This study presents a quantitative analysis of the Timepix detector for use as a soft-tissue imaging plane by evaluating varying thicknesses of tissue-equivalent plastic incorporated into a medical prostate phantom. The feasibility of using BrachyView as a diagnostic tool is established by demonstrating the resolving power and high contrast obtainable with this configuration.
Keywords: treatment planning; radiotherapy; oncology; prostate cancer; medical imaging; feasibility studies; dosimetry; diagnosis; urology; brachytherapy; imaging; low dose rate brachytherapy; prostate cancers; diseases; tissue; intra-operative; prostate brachytherapy; intraoperative; imaging techniques; functional polymers; silicon detectors; image resolution; medipix
Journal Title: Radiation Measurements
Volume: 71
ISSN: 1350-4487
Publisher: Elsevier Inc.  
Date Published: 2014-12-01
Start Page: 329
End Page: 332
Language: English
DOI: 10.1016/j.radmeas.2014.03.004
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 2 March 2015 -- Source: Scopus
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  1. Marco Zaider
    171 Zaider