Imaging techniques in desmoid tumors Book Section
| Authors: | Lefkowitz, R. A.; Hwang, S.; Landa, J. |
| Editor: | Litchman, C. |
| Article/Chapter Title: | Imaging techniques in desmoid tumors |
| Abstract: | From an imaging perspective, desmoid tumors are best classified as extra-abdominal, abdominal wall, and intra-abdominal. MRI is the imaging modality of choice for extra-abdominal desmoids, demonstrating a lesion that can be well-defined, has infiltrative margins, or a combination of both. The lesions are low in T1 signal, while T2 signal is variable, depending upon the stage of evolution. During their early growth stage, desmoid tumors are highly cellular with relatively less collagen. As a result, they are predominantly high in T2 signal with small foci of low T2 signal, and demonstrate avid contrast enhancement. As they evolve over time, the tumors become less cellular and more densely collagenous, with a resultant decrease in T2 signal intensity and enhancement, and often with a concomitant decrease in size. Radiation and medical therapy can also result in these signal changes, suggesting treatment response even in the absence of decreases in size. Abdominal wall desmoid tumors can best be imaged with MRI or CT, while intra-abdominal desmoid tumors are best imaged with CT. CT demonstrates a mass which is nearly isodense to muscle on noncontrast images and which demonstrates mild-to-moderate enhancement with intravenous contrast. CT is superior to MRI in distinguishing intra-abdominal desmoids from adjacent bowel loops, although vascular involvement can be accurately assessed with either CT or MRI. MRI is sometimes desirable to CT for imaging of intra-abdominal desmoids, particularly in patients who cannot receive iodinated contrast material, either because of allergies or impaired renal function, or in patients in whom radiation exposure is a major concern. In patients with severe renal dysfunction, intravenous contrast should not be used with MRI either because of the risk of developing nephrogenic systemic sclerosis. © Springer Science+Business Media B.V. 2012. |
| Keywords: | ultrasound; imaging; pet; ct; mri; fibromatosis; intra-abdominal; desmoid; extra-abdominal |
| Book Title: | Desmoid Tumors |
| ISBN: | 978-94-007-1684-1 |
| Publisher: | Springer |
| Publication Place: | Dordrecht, Netherlands |
| Date Published: | 2012-01-01 |
| Start Page: | 47 |
| End Page: | 75 |
| Language: | English |
| DOI: | 10.1007/978-94-007-1685-8_5 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 5 -- Export Date: 3 March 2016 -- Source: Scopus |
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