Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: A search for a uniform approach to a troubling disease Journal Article
| Authors: | Church, J.; Berk, T.; Boman, B. M.; Guillem, J.; Lynch, C.; Lynch, P.; Rodriguez-Bigas, M.; Rusin, L.; Weber, T. |
| Article Title: | Staging intra-abdominal desmoid tumors in familial adenomatous polyposis: A search for a uniform approach to a troubling disease |
| Abstract: | INTRODUCTION: Desmoid tumors are a clinical problem in 12 to 15 percent of patients with familial adenomatous polyposis. There is no predictably effective treatment for intra-abdominal desmoid tumors, which sometimes cause significant complications by their effects on the ureters or bowel. The relative rarity and the clinical heterogeneity of intra-abdominal desmoid tumors make randomized studies difficult to do. In this article a staging system is proposed to make multi-institutional studies easier. METHODS: Intra-abdominal desmoid tumors can be staged according to their size, clinical presentation and growth pattern. CONCLUSION: A way of staging intra-abdominal desmoid tumors is proposed to facilitate stratification by disease severity during collaborative studies of various treatments. © The American Society of Colon and Rectal Surgeons. |
| Keywords: | cancer chemotherapy; mutation; clinical feature; review; postoperative period; doxorubicin; side effect; alpha interferon; cancer patient; methotrexate; cancer staging; staging; neoplasm staging; imatinib; familial disease; tumor localization; dacarbazine; peritoneal neoplasms; tumor volume; bleeding; genotype; vinblastine; prescription; disease severity; preoperative period; intraoperative period; nonsteroid antiinflammatory agent; family history; clinical protocols; tamoxifen; sepsis; receptors, estrogen; receptors, progesterone; symptomatology; intestine obstruction; tumor growth; estrogen receptor; progesterone receptor; neoplasms, multiple primary; mesentery; pirfenidone; patient care planning; abdominal wall; adenomatous polyp; desmoid tumor; hydronephrosis; raloxifene; abdominal neoplasms; fibromatosis, aggressive; familial adenomatous polyposis; adenomatous polyposis coli; peritonitis; genes, apc; abdominal tumor |
| Journal Title: | Diseases of the Colon and Rectum |
| Volume: | 48 |
| Issue: | 8 |
| ISSN: | 0012-3706 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2005-08-01 |
| Start Page: | 1528 |
| End Page: | 1534 |
| Language: | English |
| DOI: | 10.1007/s10350-005-0018-8 |
| PUBMED: | 15906134 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 36" - "Export Date: 24 October 2012" - "CODEN: DICRA" - "Source: Scopus" |
