Systemic therapies for advanced pancreatic neuroendocrine tumors Journal Article
| Authors: | Raj, N.; Reidy-Lagunes, D. |
| Article Title: | Systemic therapies for advanced pancreatic neuroendocrine tumors |
| Abstract: | Pancreatic neuroendocrine tumors are an uncommon tumor type and compose 1% to 2% of all pancreatic neoplasms. They are rarely localized at presentation and are typically diagnosed in the presence of metastatic disease. The management poses a significant challenge because of the heterogeneous clinical presentations and varying degrees of aggressiveness. A variety of systemic therapies have been developed for the management of pancreatic neuroendocrine tumors, including somatostatin analogues, a select group of cytotoxic chemotherapy agents, and targeted or biological agents. This article reviews the available systemic therapy options for advanced pancreatic neuroendocrine tumors. © 2016 Elsevier Inc. |
| Keywords: | sunitinib; octreotide; everolimus; neuroendocrine tumors; carcinoid tumors; pancreatic neuroendocrine tumors; lanreotide |
| Journal Title: | Hematology/Oncology Clinics of North America |
| Volume: | 30 |
| Issue: | 1 |
| ISSN: | 0889-8588 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2016-02-01 |
| Start Page: | 119 |
| End Page: | 133 |
| Language: | English |
| DOI: | 10.1016/j.hoc.2015.09.005 |
| PROVIDER: | scopus |
| PUBMED: | 26614372 |
| PMCID: | PMC5046222 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 3 February 2016 -- Source: Scopus |
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