Emerging influence of the intestinal microbiota during allogeneic hematopoietic cell transplantation: Control the gut and the body will follow Journal Article
| Authors: | Docampo, M. D.; Auletta, J. J.; Jenq, R. R. |
| Article Title: | Emerging influence of the intestinal microbiota during allogeneic hematopoietic cell transplantation: Control the gut and the body will follow |
| Abstract: | The intestinal microbiota has many critical roles in maintaining gastrointestinal epithelial and gastrointestinal systemic immune homeostasis. This review provides insight into how allogeneic hematopoietic cell transplantation (HCT) and its associated complications and supportive care therapies affect the microbiota. Additionally, the review discusses how preservation and restoration of the microbiota might be advantageous in decreasing HCT-related morbidity and mortality. © 2015 American Society for Blood and Marrow Transplantation. |
| Keywords: | mortality; review; nonhuman; morbidity; graft versus host reaction; allogeneic hematopoietic stem cell transplantation; bacteremia; intestine flora; homeostasis; clostridium difficile; tolerance; intestine mucosa; t cell; bone marrow transplant; paneth cell; microflora; graft-versus-host disease; antimicrobial peptide; gut microbiota; intestine epithelium; il-22; human; dysbiosis; enterocyte; regenerating islet-derived iii alpha |
| Journal Title: | Biology of Blood and Marrow Transplantation |
| Volume: | 21 |
| Issue: | 8 |
| ISSN: | 1083-8791 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2015-08-01 |
| Start Page: | 1360 |
| End Page: | 1366 |
| Language: | English |
| DOI: | 10.1016/j.bbmt.2015.02.016 |
| PROVIDER: | scopus |
| PUBMED: | 25708215 |
| DOI/URL: | |
| Notes: | Export Date: 2 September 2015 -- Source: Scopus |
