Imposing specificity by regulated localization Meeting Abstract

  


Author: Ptashne, M.
Abstract Title: Imposing specificity by regulated localization
Meeting Title: 5th Annual International Conference on Computational Molecular Biology (RECOMB)
Abstract: Many biologically important enzymes - RNA polymerases, RNA splicing enzymes, ubiquinating enzymes, certain kinases and proteases - are "'regulated"' by being brought to one or another of many potential substrates by auxiliary docking proteins (e.g. transcriptional activators). These regulatory interactions require interactions between simple adhesive (but specific) surfaces. This kind of regulation is highly 'evolvable' : new and expanded meanings to signals are readily generated by simple changes in protein surfaces.
Keywords: rna; molecular biology; enzymes; substrates; adhesion; auxillary docking proteins; regulated localization
Journal Title: RECOMB 2001: Proceedings of the Annual International Conference on Computational Molecular Biology
Meeting Dates: 2001 Apr 22-25
Meeting Location: Montréal, Canada
ISSN: 1581133537
Publisher: Assoc Computing Machinery  
Date Published: 2001-01-01
Start Page: 268
Language: English
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-0034824673&partnerID=40&md5=64e8fdc720f7a49de03a717567dfd68f
Notes: Meeting abstract -- Source: Scopus