Managing intrathecal drug delivery (ITDD) in cancer patients Journal Article


Authors: Shah, R.; Baqai-Stern, A.; Gulati, A.
Article Title: Managing intrathecal drug delivery (ITDD) in cancer patients
Abstract: Pain is a commonly reported symptom in cancer patients. Patients with cancer pain often fail conservative medical management or have significant side effects to systemic medications. The implantation of an intrathecal drug delivery (ITDD) system may be the most effective treatment option for these patients and can improve their quality of life. This article aims to discuss the choice of intrathecal medications for patients suffering from intractable cancer pain, the management of ITDD throughout a patient’s disease course, and the management of complications related to the ITDD system and intrathecal medications. © 2015, Springer Science+Business Media New York.
Keywords: treatment response; disease course; review; cancer combination chemotherapy; drug efficacy; drug potentiation; drug safety; quality of life; neutrophil count; cancer pain; patient monitoring; radiation exposure; hypotension; narcotic analgesic agent; cardiotoxicity; patient safety; patient compliance; thrombocyte count; seizure; headache; drug bioavailability; sensory dysfunction; morphine; respiration depression; lidocaine; immune deficiency; motor dysfunction; seroma; neurologic disease; bupivacaine; hydromorphone; pain assessment; urine retention; visual analog scale; neuropathic pain; infection risk; functional status; radiofrequency; hyperalgesia; fentanyl; intractable pain; inflammatory disease; drug choice; clonidine; omega conotoxin mviia; hypogonadotropic hypogonadism; hypersensitivity; phrenic nerve paralysis; bacterial meningitis; sufentanil; hygroma; medical device complication; neuraxial trial; human; intrathecal drug delivery; intrathecal drug delivery system; nociceptive pain; drug delivery device; intrathecal medications; ropivacaine; tetracaine; intrathecal catheter; intrathecal granuloma; numeric rating scale
Journal Title: Current Pain and Headache Reports
Volume: 19
Issue: 6
ISSN: 1531-3433
Publisher: Springer  
Date Published: 2015-05-01
Start Page: 20
Language: English
DOI: 10.1007/s11916-015-0488-x
PROVIDER: scopus
PUBMED: 26021753
DOI/URL:
Notes: Export Date: 2 July 2015 -- Source: Scopus
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  1. Amitabh Gulati
    155 Gulati
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