Considerations for evaluating the use of intrathecal drug delivery in the oncologic patient Journal Article

  


Authors: Gulati, A.; Puttanniah, V.; Hung, J.; Malhotra, V.
Article Title: Considerations for evaluating the use of intrathecal drug delivery in the oncologic patient
Abstract: While the majority of cancer pain patients are successfully managed with conservative medical management, some patients may suffer from intractable pain or intolerable side effects. The implantation of an intrathecal drug delivery system offers many advantages to improve both analgesia and side effect profile. Practitioners may decide to proceed toward implantation after appropriate patient selection, and, when applicable, a suitable trial for the device. Once implantation is completed, multiple medication combinations may be used to optimize the therapeutic benefit of the device. We describe a stepwise paradigm to implement an intrathecal drug delivery program in the cancer pain population. © 2014 Springer Science+Business Media New York.
Keywords: treatment response; constipation; drug tolerability; drug dose reduction; drug efficacy; drug safety; drug withdrawal; patient selection; cancer patient; outcome assessment; quality of life; tumor volume; nausea; midazolam; cancer pain; patient assessment; risk factor; risk assessment; drug dose escalation; pruritus; narcotic analgesic agent; total quality management; conservative treatment; drug response; perioperative period; clinical effectiveness; morphine; drug dose titration; neurologic disease; bupivacaine; hydromorphone; analgesia; pain assessment; urine retention; drug delivery system; analgesic agent; granuloma; fentanyl; ketamine; clonidine; omega conotoxin mviia; sufentanil; baclofen; intrathecal pump; human; article; intrathecal drug delivery; oncologic patient; side effect profile; intrathecal drug delivery system
Journal Title: Current Pain and Headache Reports
Volume: 18
Issue: 2
ISSN: 1531-3433
Publisher: Springer  
Date Published: 2014-01-01
Start Page: 391
Language: English
DOI: 10.1007/s11916-013-0391-2
PROVIDER: scopus
PUBMED: 24407749
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84896714051&partnerID=40&md5=536e1686d1e360ec90d4138812ab107a
Notes: Export Date: 1 May 2014 -- CODEN: CPHRG -- Source: Scopus
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MSK Authors
  1. Amitabh Gulati
    155 Gulati
  2. Vivek Malhotra
    28 Malhotra
  3. Vinay Ganesh Puttanniah
    25 Puttanniah
  4. Joseph C Hung
    14 Hung
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