Intrathecal drug delivery systems survey: Trends in utilization in pain practice Journal Article


Authors: Abd-Sayed, A.; Fiala, K.; Weibstein, J.; Chopra, P.; Lam, C.; Kalia, H.; Jassal, N.; Gulati, A.; Sayed, D.; Deer, T.
Article Title: Intrathecal drug delivery systems survey: Trends in utilization in pain practice
Abstract: Background: The use of intrathecal drug delivery for chronic and cancer pain medicine has been established for decades. However, optimization and utilization of this technique still lag behind other modalities for pain control. Some of this may be due to variability of surgical technique, medication usage and education. It is currently unclear on whether or not practitioners follow available algorithms for the use of intrathecal drug delivery systems. Methods: A survey developed by the American Society of Pain and Neuroscience (ASPN) was sent to its members via email using the cloud-based SurveyMonkey. After 30 days of being available, 159 different providers responded to the survey that consisted of 31 various multiple choice and free response questions. Each question was not required and the number of responses to each varied from 128 to 159. Results: Approximately 9% of those who successfully received and opened the email containing the survey responded, likely due to a small number of providers working with intrathecal drug delivery systems. Eighty-six of respondents practice medicine in the United States, and 87% of the respondents were attending physicians. A majority of respondents, approximately 74%, were board certified in pain medicine with 69% of respondents being train in anesthesiology. The first and second most used medications for intrathecal pump trial were morphine and fentanyl, respectively. Most respondents, approximately 96%, provide pre-operative/intra-operative antibio-tics. The most common first-choice medication for implanted intrathecal pumps was also morphine with the most common implanted location being the abdomen. Conclusion: Interestingly, there is currently fairly substantial variation in the way providers utilize intrathecal pump delivery for both chronic and cancer pain. There is variation from the training background of the providers providing care, to the pre-implantation trial medications, to where the pump is implanted for each patient, to if the patient has the option to give themselves boluses once implanted. Further research is needed to elucidate current and best practices for intrathecal drug delivery system trials, implantations, and utilization. © 2022 Abd-Sayed et al.
Keywords: adult; aged; middle aged; antibiotic agent; united states; preoperative care; treatment indication; infection; pain; cancer pain; neuromodulation; pruritus; health care utilization; sexual dysfunction; abdomen; medical education; medical practice; physician; chronic pain; morphine; respiration depression; trend study; seroma; antibiotic prophylaxis; hydromorphone; analgesia; urine retention; neuropathic pain; liquorrhea; meningitis; drug delivery system; peroperative care; skin infection; pain management; fentanyl; omega conotoxin mviia; nurse practitioner; intrathecal; physician assistant; contusion; baclofen; medical device complication; human; male; female; article; intrathecal drug delivery system; anesthesiology; postdural puncture headache; pump infection; pump failure; sexual insufficiency
Journal Title: Journal of Pain Research
Volume: 15
ISSN: 1178-7090
Publisher: Dove Medical Press Ltd  
Date Published: 2022-01-01
Start Page: 1305
End Page: 1314
Language: English
DOI: 10.2147/jpr.S344409
PROVIDER: scopus
PMCID: PMC9078357
PUBMED: 35535265
DOI/URL:
Notes: Article -- Export Date: 1 July 2022 -- Source: Scopus
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  1. Amitabh Gulati
    146 Gulati
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