Genome-wide gene expression analysis of prostate carcinoma Journal Article
| Author: | Gerald, W. L. |
| Article Title: | Genome-wide gene expression analysis of prostate carcinoma |
| Abstract: | Advances in our knowledge of the molecular basis of prostate cancer have the potential to improve patient care and outcome. The investigative pace has recently been dramatically enhanced by the availability of the complete human genome sequence and the development of high-throughput technology for comprehensive genetic analysis. The application of genomic scale analysis to the study of prostate cancer has resulted in significant successes, including methods of more precise diagnosis and identification of potential prognostic markers and therapeutic targets. It is clear that these novel technologies and approaches provide many opportunities for biologists and clinicians; however, there are many challenges in moving these discoveries forward. © 2003 Elsevier Inc. All rights reserved. |
| Keywords: | gene sequence; review; cancer incidence; diagnostic accuracy; genetic analysis; gene expression; gene expression profiling; tumor markers, biological; genetic transcription; drug resistance, neoplasm; tumor marker; cancer hormone therapy; prostatic neoplasms; cancer genetics; gene expression regulation, neoplastic; oligonucleotide array sequence analysis; human genome; androgen antagonists; antiandrogen; receptors, androgen; up-regulation; technology; genome, human; prostate carcinoma; chromosome mapping; humans; prognosis; human; male; priority journal |
| Journal Title: | Seminars in Oncology |
| Volume: | 30 |
| Issue: | 5 |
| ISSN: | 0093-7754 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2003-10-01 |
| Start Page: | 635 |
| End Page: | 648 |
| Language: | English |
| DOI: | 10.1016/s0093-7754(03)00349-x |
| PUBMED: | 14571411 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 25 September 2014 -- Source: Scopus |
