Pancreatic neuroendocrine paraneoplastic optic neuropathy: Confirmation with antibody to optic nerve and hepatic metastasis Journal Article


Authors: Slamovits, T. L.; Posner, J. B.; Reidy, D. L.; Thirkill, C. E.; Keltner, J. L.
Article Title: Pancreatic neuroendocrine paraneoplastic optic neuropathy: Confirmation with antibody to optic nerve and hepatic metastasis
Abstract: A 68-year-old woman presented with bilateral visual loss as the only clinical manifestation of an occult pancreatic nonsecretory neuroendocrine tumor (NET). The suspected diagnosis of paraneoplastic optic neuropathy was confirmed using immunofluorescence assays to demonstrate the presence of antibodies in the patient's serum that reacted with antigen(s) in the optic nerve and in the pancreatic NET hepatic metastasis. Treatment of the underlying cancer was followed by marked improvement in visual function. © 2012 by North American Neuro-Ophthalmology Society.
Journal Title: Journal of Neuro-Ophthalmology
Volume: 33
Issue: 1
ISSN: 1070-8022
Publisher: Lippincott Williams & Wilkins  
Date Published: 2013-03-01
Start Page: 21
End Page: 25
Language: English
DOI: 10.1097/WNO.0b013e3182699b2a
PROVIDER: scopus
PUBMED: 22926698
DOI/URL:
Notes: --- - "Export Date: 1 March 2013" - "CODEN: JNEOE" - "Source: Scopus"
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  1. Diane Lauren Reidy
    294 Reidy
  2. Jerome B Posner
    211 Posner