Bartonella quintana Endocarditis in persons experiencing homelessness, New York, New York, USA, 2020–2023 Journal Article
| Authors: | Keller, M.; Agladze, M.; Kupferman, T.; Rich, S. N.; Marx, G. E.; Gnanaprakasam, R.; Kodama, R.; Feldmesser, M.; Mitchell, K.; Wroblewski, D.; Juretschko, S.; Kleinman, G. M.; Kuehnert, M. J.; Bhatnagar, J.; Carnes, M. D.; Bullock, H.; Reagan-Steiner, S.; Corvese, G.; Ackelsberg, J. |
| Article Title: | Bartonella quintana Endocarditis in persons experiencing homelessness, New York, New York, USA, 2020–2023 |
| Abstract: | Bartonella quintana infection can lead to bacillary angiomatosis, peliosis hepatis, chronic bacteremia, and culture-negative endocarditis. Transmitted by the human body louse (Pediculus humanus humanus), B. quintana infection has become an emerging disease in recent decades among persons experiencing homelessness. By using retrospective laboratory surveillance, we identified 5 cases of left-sided, culture-negative B. quintana endocarditis among persons in New York, New York, USA, during January 1, 2020–November 23, 2023. Identifications were made by using molecular assays. All patients experienced unsheltered homelessness in the year before hospitalization. Of those patients, 4 experienced heart failure, 3 renal failure, and 2 embolic strokes; 2 died. Aortic valve replacement occurred in 4 cases. A history of possible body louse infestation was found in 4 cases. Clinicians should consider housing status and history of lice exposure in patients with suspected bartonellosis and have a low threshold for diagnostic testing and empiric treatment in patients experiencing homelessness. © 2024 Centers for Disease Control and Prevention (CDC). All rights reserved. |
| Keywords: | adult; clinical article; aged; middle aged; retrospective studies; genetics; case report; diarrhea; hypertension; nuclear magnetic resonance imaging; polymerase chain reaction; animal; electron microscopy; animals; anemia; thrombocytopenia; kidney failure; retrospective study; hematuria; dyspnea; acute kidney failure; hypoalbuminemia; electronic medical record; hospitalization; heart failure; diagnosis; hyperpigmentation; glomerulonephritis; bacteremia; hemangiomatosis; vancomycin; epidemiology; echocardiography; microbiology; doxycycline; new york; blood clotting disorder; rna 16s; isolation and purification; azithromycin; hemodialysis; leukocytosis; brain hemorrhage; brain natriuretic peptide; computed tomographic angiography; schizophrenia; ceftriaxone; alcoholism; pulmonary hypertension; reflex bradycardia; bacterial endocarditis; bipolar disorder; daptomycin; personality disorder; metabolic acidosis; enterococcus faecalis; endocarditis; high throughput sequencing; diastolic dysfunction; mitral valve regurgitation; dna sequencing; bartonella; humans; human; male; female; article; cardioembolic stroke; endocarditis, bacterial; homelessness; bacillary angiomatosis; mycotic aneurysm; trench fever; clostridioides difficile; aortic valve replacement; homeless person; aortic regurgitation; bartonella quintana; ill-housed persons; aortic leaflet; bartonellosis; lung congestion; pediculus humanus corporis; peliosis hepatis; reflex tachycardia |
| Journal Title: | Emerging Infectious Diseases |
| Volume: | 30 |
| Issue: | 12 |
| ISSN: | 1080-6040 |
| Publisher: | Centers for Disease Control and Prevention |
| Date Published: | 2024-12-01 |
| Start Page: | 2494 |
| End Page: | 2501 |
| Language: | English |
| DOI: | 10.3201/eid3012.240433 |
| PUBMED: | 39592252 |
| PROVIDER: | scopus |
| PMCID: | PMC11616645 |
| DOI/URL: | |
| Notes: | Source: Scopus |
