Prevalence of PPD positivity among new employees at a hospital in New York City Journal Article


Authors: Sepkowitz, K. A.; Fella, P.; Rivera, P.; Villa, N.; DeHovitz, J.
Article Title: Prevalence of PPD positivity among new employees at a hospital in New York City
Abstract: OBJECTIVE: To determine the prevalence of tuberculin reactivity among all new employees at a hospital in New York City. DESIGNS: Prospective measurement of purified protein derivative (PPD) status in consecutive new employees at a hospital in New York City from 1991 to 1993. All employees are tested as part of a pre-employment physical, assuring complete compliance. Aplisol (Parke-Davis, Morris Plains, NJ) was used in 1991 and 1992, and Tùbersol (Connaught, Swiftwater, PA) in 1993. Tests were applied and interpreted by trained employee health personnel. RESULTS: Of 313 consecutive new employees, comprising all job categories, 40% were PPD positive at time of initial hire, including 20% of US-bom and 70% of foreign-bom employees. Of 114 persons who had received BCG vaccination, 67% were PPD positive. By multivariate regression analysis, age, BCG vaccination history, and foreign country of birth were independent predictors of a reactive PPD test. CONCLUSIONS: The high prevalence of tuberculin reactivity may reflect high rates of Mycobacterium tuberculosis infection and disease in the community, complicating interpretation of the efficacy of Centers for Disease Control and Prevention (CDC) guidelines to prevent the spread of tuberculosis in healthcare facilities. © 1995, The Society for Healthcare Epidemiology of America. All rights reserved.
Keywords: adolescent; adult; united states; bcg vaccine; prevalence; new york city; hospital personnel; middle age; lung tuberculosis; tuberculin test; tuberculosis, pulmonary; human; male; female; article; personnel, hospital
Journal Title: Infection Control and Hospital Epidemiology
Volume: 16
Issue: 6
ISSN: 0899-823X
Publisher: The Society for Healthcare Epidemiology of America  
Date Published: 1995-06-01
Start Page: 344
End Page: 347
Language: English
DOI: 10.1086/647123
PUBMED: 7657987
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
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  1. Kent A Sepkowitz
    273 Sepkowitz