Benefit of two-step PPD testing of new employees at a New York City hospital Journal Article


Authors: Sepkowitz, K. A.; Feldman, J.; Louther, J.; Rivera, P.; Villa, N.; DeHovitz, J.
Article Title: Benefit of two-step PPD testing of new employees at a New York City hospital
Abstract: Background: Recent concern about nosocomial transmission of tuberculosis has led hospitals to scrutinize employee tuberculin conversion rates. The Centers for Disease Control and Prevention recommends two-step testing of new employees to limit the booster phenomenon. The cost of such a program and its subsequent yield have not recently been examined. Methods: Employee health records were retrospectively reviewed of persons hired from 1993 and 1994 at St. Clare's Hospital in New York City, all of whom received two-step testing at time of initial employment. Results: Of 262 new employees, 107 (41%) had positive tuberculin results on initial testing. The results of 15 (9.7%) of the remaining 155 patients became positive on two-step testing administered 1 week later. Persons with a positive second test result were significantly more likely to be male or foreign born or to have received previous bacille Calmette-Guerin vaccination. Identification of these 15 persons and exclusion of them from probable subsequent conversion prevented an almost 50% increase in the annual conversion rate at our hospital, from 3.2% to 4.7%. Conclusion: Two-step tuberculin testing is an essential means of identifying persons with a baseline positive tuberculin test result, thus allowing accurate reporting of subsequent employee tuberculin conversions.
Keywords: adult; human tissue; human cell; united states; bcg vaccine; practice guideline; cost effectiveness analysis; health care cost; mycobacterium tuberculosis; diagnostic value; mycobacterium bovis; new york city; hospital infection; guidelines; tuberculosis; cross infection; centers for disease control and prevention (u.s.); bcg vaccination; employment; tuberculin test; occupational hazard; tuberculosis, pulmonary; humans; human; male; female; article; personnel, hospital; hospital bed capacity, 100 to 299; employability
Journal Title: American Journal of Infection Control
Volume: 25
Issue: 3
ISSN: 0196-6553
Publisher: Elsevier Inc.  
Date Published: 1997-06-01
Start Page: 283
End Page: 286
Language: English
DOI: 10.1016/s0196-6553(97)90015-8
PUBMED: 9202825
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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  1. Kent A Sepkowitz
    272 Sepkowitz