Morphological features of basal cell carcinoma on ex vivo confocal imaging and histopathologic correlation Book Section
| Authors: | Sendín-Martín, M.; Harris, U.; Moronta, M.; Pulitzer, M.; Lee, E.; Rossi, A.; Chen, C. S. J.; Nehal, K.; Jain, M. |
| Editors: | Jain, M.; Rossi, A.; Nehal, K.; Sendín-Martín, M. |
| Article/Chapter Title: | Morphological features of basal cell carcinoma on ex vivo confocal imaging and histopathologic correlation |
| Abstract: | Basal cell carcinoma is the most common skin cancer worldwide. Mohs micrographic surgery (MMS) is a specialized surgical procedure to treat and achieve complete clearance of BCCs. However, frozen sectioning performed during MMS is a time-consuming and a labor-intensive process. Ex vivo confocal microscopy (EVCM) is an attractive alternative to frozen sectioning during MMS as it can rapidly image fresh (unprocessed and un-sectioned) tissue, enabling tumor margin assessment in real-time. EVCM has shown high sensitivity and specificity for detecting BCCs. In this chapter, we have described the morphological features of common subtypes of BCC as visualized in various imaging modes on the EVCM (fluorescence confocal microscopy and digital H&E mode) and compared them with their corresponding. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022. |
| Keywords: | basal cell carcinoma; histopathologic correlation; fluorescence confocal microscopy; ex vivo confocal microscopy; digital h&e |
| Book Title: | Cutaneous Atlas of Ex Vivo Confocal Microscopy |
| ISBN: | 978-3-030-89315-6 |
| Publisher: | Springer Nature |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2022-01-01 |
| Start Page: | 81 |
| End Page: | 95 |
| Language: | English |
| DOI: | 10.1007/978-3-030-89316-3_7 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter: 7 -- Located in "Part IV: Malignant Keratinocyte Neoplasms" Source: Scopus |
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