Dosimetry in radiopharmaceutical therapy Review

  


Authors: O'Donoghue, J.; Zanzonico, P.; Humm, J.; Kesner, A.
Review Title: Dosimetry in radiopharmaceutical therapy
Abstract: The application of radiopharmaceutical therapy for the treatment of certain diseases is well established, and the field is expanding. New therapeutic radiopharmaceuticals have been developed in recent years, and more are in the research pipeline. Concurrently, there is growing interest in the use of internal dosimetry as a means of personalizing, and potentially optimizing, such therapy for patients. Internal dosimetry is multifaceted, and the current state of the art is discussed in this continuing education article. Topics include the context of dosimetry, internal dosimetry methods, the advantages and disadvantages of incorporating dosimetry calculations in radiopharmaceutical therapy, a description of the workflow for implementing patient-specific dosimetry, and future prospects in the field. © 2022 by the Society of Nuclear Medicine and Molecular Imaging.
Keywords: radiopharmaceuticals; dosimetry; radiopharmaceutical agent; radiometry; radiobiology; alpha particles; procedures; radionuclide therapy; radiopharmaceutical; humans; human; auger electrons
Journal Title: Journal of Nuclear Medicine
Volume: 63
Issue: 10
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2022-10-01
Start Page: 1467
End Page: 1474
Language: English
DOI: 10.2967/jnumed.121.262305
PUBMED: 36192334
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139150734&doi=10.2967%2fjnumed.121.262305&partnerID=40&md5=2ebfe5ca12cd5ead9fb97cae51ae34f4
Notes: Article -- Export Date: 1 November 2022 -- Source: Scopus
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MSK Authors
  1. Joseph O'Donoghue
    151 O'Donoghue
  2. John Laurence Humm
    433 Humm
  3. Pat B Zanzonico
    355 Zanzonico
  4. Adam Leon Kesner
    68 Kesner
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