Dosimetry in radiopharmaceutical therapy Book Section
| Authors: | Carter, L. M.; Kesner, A. L. |
| Editors: | Bodei, L.; Lewis, J. S.; Zeglis, B. M. |
| Article/Chapter Title: | Dosimetry in radiopharmaceutical therapy |
| Abstract: | The foundational principle of radiopharmaceutical therapy (RPT) is to deliver tissue-altering radiation to diseased tissue while minimizing damage to healthy tissue. The utility and efficacy of a targeted radiotherapeutic procedure arise from the interplay between the physiological distribution of a radiopharmaceutical, the emitted particles of the associated radionuclide, the subject’s anatomy, and radiobiologic factors. The characterization of this multifactorial paradigm is encapsulated in the field of internal dosimetry. Through dosimetry, we quantify the distribution and strength of the intervention in terms of radiation dose deposition. This information supports clinicians in predicting and optimizing treatment outcomes. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023. |
| Keywords: | treatment planning; pharmacokinetics; mird; radiopharmaceutical therapy; internal dosimetry; emission imaging |
| Book Title: | Radiopharmaceutical Therapy |
| ISBN: | 978-3-031-39004-3 |
| Publisher: | Springer |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2023-01-01 |
| Start Page: | 173 |
| End Page: | 190 |
| Language: | English |
| DOI: | 10.1007/978-3-031-39005-0_8 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book chapter: 8 -- Source: Scopus |
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