Neurocutaneous melanocytosis-associated malignant melanoma presenting with peritoneal seeding Journal Article


Authors: Sener, U.; Elmore, K.; Jayaseelan, K.; Porter, J.; Marghoob, A.; Rosenblum, M. K.; Haque, S.; Khakoo, Y.
Article Title: Neurocutaneous melanocytosis-associated malignant melanoma presenting with peritoneal seeding
Abstract: Neurocutaneous melanocytosis (NCM) is characterized by melanocyte deposition in the leptomeninges and brain parenchyma, primarily occurring in children with large or giant congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi. Patients with NCM may develop hydrocephalus and increased intracranial pressure, which can be managed with ventriculoperitoneal (VP) shunting. We present the case of a 16-month-old girl who developed peritoneal carcinomatosis and malignant ascites following VP shunting for hydrocephalus secondary to NCM to increase awareness of this rare, but serious, complication of cerebrospinal fluid diversion. © 2021 Wiley Periodicals LLC.
Keywords: meningeal carcinomatosis; peritoneal carcinomatosis; neoplasms malignant; neurocutaneous disorders; nevi-melanocytic
Journal Title: Pediatric Dermatology
Volume: 38
Issue: 5
ISSN: 0736-8046
Publisher: Blackwell Scientific Publications  
Date Published: 2021-09-01
Start Page: 1298
End Page: 1301
Language: English
DOI: 10.1111/pde.14789
PUBMED: 34463389
PROVIDER: scopus
PMCID: PMC9429811
DOI/URL:
Notes: Article -- Export Date: 1 December 2021 -- Source: Scopus
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MSK Authors
  1. Yasmin Khakoo
    149 Khakoo
  2. Marc Rosenblum
    424 Rosenblum
  3. Sofia S Haque
    148 Haque
  4. Ashfaq A Marghoob
    534 Marghoob
  5. Kevin Bradford Elmore
    4 Elmore