Central and peripheral nervous system complications of AIDS Journal Article

  


Authors: Navia, B. A.; Price, R. W.
Article Title: Central and peripheral nervous system complications of AIDS
Abstract: The acquired immune deficiency syndrome (AIDS) may be complicated by a variety of central nervous system (CNS) and peripheral nervous system (PNS) disorders, which include opportunistic infections (e.g. cerebral toxoplasmosis, progressive multifocal leukoencephalopathy (PML), cryptococcal meningitis), opportunistic neoplasms (e.g. primary CNS lymphoma), disorders unique to AIDS (e.g. the AIDS dementia complex and associated vacuolar myelopathy) and immunopathological injury (e.g. inflammatory demyelinating polyneuropathies). The frequency of these disorders ranges from that of the AIDS dementia complex which may eventually afflict the majority of AIDS patients, to toxoplasmosis which develops in as many as 10% of patients, to uncommon disorders such as PML which occurs in about 2% of patients, to a heterogeneous group of rare complications such as direct brain involvement by Kaposi's sarcoma. Although AIDS is a progressive lethal disease, accurate neurological diagnosis and, when possible, prompt therapy, can alleviate some of the morbidity of the disease and prolong meaningful survival.
Keywords: review; neuropathy; central nervous system; lymphoma; dementia; progressive multifocal leukoencephalopathy; acquired immune deficiency syndrome; encephalitis; meningitis; peripheral nervous system; human immunodeficiency virus 1; nervous system; toxoplasmosis; cryptococcosis; human
Journal Title: Clinics in Immunology and Allergy
Volume: 6
Issue: 3
ISSN: 0260-4639
Publisher: Elsevier Inc.  
Date Published: 1986-10-01
Start Page: 543
End Page: 558
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022980357&partnerID=40&md5=e69d18218940faf2b1ee511c585afc78
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus