The AIDS dementia complex: Some current questions Conference Paper
| Authors: | Price, R. W.; Sidtis, J.; Rosenblum, M. |
| Title: | The AIDS dementia complex: Some current questions |
| Conference Title: | Retroviruses in the Nervous System |
| Abstract: | The acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) commonly complicates the course of human immunodeficiency virus (HIV) infection and AIDS. Although many of its clinical aspects have recently been brought into clearer focus, and pathogenetic evidence has accrued implicating direct HIV brain infection, there remain a number of fundamental aspects of ADC and HIV nervous system infection that require clarification. These include clearer definition of the clinical syndrome and its variants; development of instrumentation for diagnosis and monitoring the disorder; definition of the epidemiology and natural history of both central nervous system HIV infection and ADC, which may seemingly be discordant; and understanding of both the viral pathogenesis and the biology of resultant brain dysfunction. Elucidation of these fundamental issues will enhance rational development and evaluation of therapy. Copyright © 1988 American Neurological Association |
| Keywords: | adult; review; psychological aspect; brain; meninges; dementia; cognition; human immunodeficiency virus; acquired immunodeficiency syndrome; epidemiology; autopsy; intravenous drug administration; terminology; central nervous system diseases; aids related complex; human; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
| Journal Title | Annals of Neurology |
| Volume: | 23 |
| Issue: | Suppl. 1 |
| Conference Dates: | 1987 May 4-6 |
| Conference Location: | Bethesda, MD |
| ISBN: | 0364-5134 |
| Publisher: | Wiley Blackwell |
| Date Published: | 1988-01-01 |
| Start Page: | S27 |
| End Page: | S33 |
| Language: | English |
| DOI: | 10.1002/ana.410230711 |
| PUBMED: | 3348598 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus |
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