Immunotherapeutic strategies in breast cancer: A clinical update Review

   


Authors: Zhang, J. Q.; Plitas, G.
Review Title: Immunotherapeutic strategies in breast cancer: A clinical update
Abstract: Immunotherapy has been incorporated into the standard of care for a wide range of malignancies. The study of tumor-infiltrating lymphocytes has emphasized the importance of the host antitumor immune response in the natural history of breast cancer. Recent clinical trials have used immunotherapeutic approaches to augment this response and improve outcomes for patients with breast cancer. Here, we review several current clinical trial data that indicate checkpoint blockade may mediate clinically significant responses. © 2020 Wiley Periodicals LLC
Keywords: review; advanced cancer; paclitaxel; neoadjuvant therapy; tumor associated leukocyte; lymphocytes, tumor-infiltrating; cancer immunotherapy; breast cancer; randomized controlled trials as topic; breast neoplasms; immunology; immunotherapy; breast tumor; toxicity; metastatic breast cancer; outcomes; randomized controlled trial (topic); clinical trial (topic); procedures; checkpoint blockade; humans; human; female; priority journal; pembrolizumab; immune checkpoint inhibitors; atezolizumab; avelumab
Journal Title: Journal of Surgical Oncology
Volume: 123
Issue: 3
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2021-03-01
Start Page: 710
End Page: 717
Language: English
DOI: 10.1002/jso.26287
PUBMED: 33155281
PROVIDER: scopus
PMCID: PMC7889634
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096639544&doi=10.1002%2fjso.26287&partnerID=40&md5=3dda781db6f3f9145a95efd9b83a48c3
Notes: Review -- Export Date: 1 April 2021 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. George Plitas
    107 Plitas
  2. Jennifer Qi Zhang
    27 Zhang
Related MSK Work