Author: | Dhawan, V. |
Article Title: | Model for (82)Sr/(82)Rb generator elution profiles: A secondary approach to radioassay/dosimetry |
Abstract: | Static (dose calibrator) assays of 82Rb bolus yield erroneous estimates of administered activity by ignoring the asymmetric output of 82Sr/82Rb generators. Though on-line monitoring of elution profile improves accuracy for quantitative purposes, it requires an elaborately shielded detector and associated electronics at patient-study site. Our alternative approach based on mathematical description of the dynamic characteristics of the generator accurately predicts elution profiles over a broad range of flow rates. © 1987. |
Keywords: | nonhuman; radiation dose; biological model; models, biological; radiation dosage; mathematical model; diagnostic agent; tissue distribution; dosimetry; radioactivity; computer assisted emission tomography; drug dose; radioisotope; radioisotopes; drug determination; tomography, emission-computed; rubidium 82; radionuclide generators; radioassay; biomedical equipment; strontium; nonbiological model; rubidium; human; article; strontium 82; drug analysis; rubidium - isotopes; elution profile; rubidium-82 |
Journal Title: | International Journal of Radiation Applications and Instrumentation. Part A: Applied Radiation and Isotopes |
Volume: | 38 |
Issue: | 3 |
ISSN: | 0883-2889 |
Publisher: | Elsevier, Inc. |
Date Published: | 1987-01-01 |
Start Page: | 233 |
End Page: | 239 |
Language: | English |
DOI: | 10.1016/0883-2889(87)90093-1 |
PUBMED: | 3034831 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |