Technical and nidus-specific factors associated with adequacy of intraprocedural biopsy samples preceding radiofrequency ablation of osteoid osteoma Journal Article
| Authors: | Soliman, M. M.; Aguado, A.; Sutton, C.; Hameed, M.; Hwang, S.; Healey, J. H.; Maybody, M. |
| Article Title: | Technical and nidus-specific factors associated with adequacy of intraprocedural biopsy samples preceding radiofrequency ablation of osteoid osteoma |
| Abstract: | Purpose: To examine the diagnostic yield of intraprocedural percutaneous biopsy performed at the time of radiofrequency ablation of suspected Osteoid Osteoma (OO) and identify technical and nidus-specific factors associated with diagnostic adequacy. Materials and methods: Following IRB approval, a total of 42 patients (male: 28, female: 14; mean age: 29 years) who underwent intraprocedural biopsy immediately prior to RFA between June 2010 and June 2017 were retrospectively identified. The nidi were located in various locations. The nidi had a mean size of 6.3 mm (range: 3–11 mm, Standard deviation (SD): 2.26). Core biopsies were performed by one of 15 operators. Biopsies were performed with two needle types ranging from 11-G to 15-G with a mean number of samples of 1.8 (range: 1–5, SD: 1.01). Electronic records and imaging were reviewed for demographics, nidus characteristics, biopsy details and diagnostic yield. Multivariate logistic regression of nidus-specific and biopsy-specific factors was performed. Results: A total of 22/42 (52.3%) of the biopsies were adequate for histological diagnosis of OO. For the two experienced operators, the diagnostic yield was 67% (6/9) and 80% (8/10). Biopsy adequacy was significantly correlated with presence of an osteoid matrix (p = 0.03), obtaining >1 core sample (p = 0.03), the needle track passing through the nidus (p = 0.0003) and thinner (2.5 mm) intraprocedural CT slices (p = 0.03). On multivariate analysis, use of thinner intraprocedural CT slices was found to be associated with adequate biopsy (p = 0.02). Conclusion: Intraprocedural percutaneous biopsy samples of nidi highly-suspected to be OO at the time of RFA were diagnostic in 52% of patients. Multivariate analysis shows thinner intraprocedural CT slices to be a significantly associated with biopsy adequacy. © 2020 Elsevier Inc. |
| Keywords: | adult; clinical article; histopathology; diagnostic imaging; medical record review; biopsy; diagnostic value; computerized tomography; needle biopsy; radiofrequency ablation; multi variate analysis; multivariant analysis; percutaneous biopsy; needles; image-guided; percutaneous; ablation; radio-frequency ablation; standard deviation; osteoid osteoma; image-guided biopsy; human; male; female; priority journal; article; diagnostic yield; multivariate logistic regressions |
| Journal Title: | Clinical Imaging |
| Volume: | 61 |
| ISSN: | 0899-7071 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-05-01 |
| Start Page: | 27 |
| End Page: | 32 |
| Language: | English |
| DOI: | 10.1016/j.clinimag.2020.01.010 |
| PUBMED: | 31954348 |
| PROVIDER: | scopus |
| PMCID: | PMC7085978 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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