Author: | DeAngelis, L. M. |
Article Title: | Primary central nervous system lymphoma imitates multiple sclerosis |
Abstract: | Primary central nervous system lymphoma (PCNSL) can be confused with multiple sclerosis (MS) in patients who present with neurological dysfunction, a non-enhancing periventricular lesion, and CSF pleocytosis. Administration of corticosteroid causes clinical improvement and regression of PCNSL in some patients which may be interpreted as a steroid-induced remission from an exacerbation of MS. Sustained clinical dependance upon corticosteroid is unusual in MS, and should lead to consideration of PCNSL. Repeat CSF examination and gadolinium-enhanced MRI scan obtained off corticosteroid should differentiate between the two diagnostic possibilities. © 1990 Kluwer Academic Publishers. |
Keywords: | prednisone; case report; brain neoplasms; magnetic resonance imaging; diagnosis, differential; tomography, x-ray computed; non-hodgkin's lymphoma; lymphoma; multiple sclerosis; nuclear magnetic resonance; brain neoplasm; middle age; human; male; article |
Journal Title: | Journal of Neuro-Oncology |
Volume: | 9 |
Issue: | 2 |
ISSN: | 0167-594X |
Publisher: | Springer |
Date Published: | 1990-10-01 |
Start Page: | 177 |
End Page: | 181 |
Language: | English |
DOI: | 10.1007/bf02427840 |
PUBMED: | 2262803 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 27 January 2020 -- Source: Scopus |