Primary central nervous system lymphoma imitates multiple sclerosis Journal Article


Author: DeAngelis, L. M.
Article Title: Primary central nervous system lymphoma imitates multiple sclerosis
Abstract: Primary central nervous system lymphoma (PCNSL) can be confused with multiple sclerosis (MS) in patients who present with neurological dysfunction, a non-enhancing periventricular lesion, and CSF pleocytosis. Administration of corticosteroid causes clinical improvement and regression of PCNSL in some patients which may be interpreted as a steroid-induced remission from an exacerbation of MS. Sustained clinical dependance upon corticosteroid is unusual in MS, and should lead to consideration of PCNSL. Repeat CSF examination and gadolinium-enhanced MRI scan obtained off corticosteroid should differentiate between the two diagnostic possibilities. © 1990 Kluwer Academic Publishers.
Keywords: prednisone; case report; brain neoplasms; magnetic resonance imaging; diagnosis, differential; tomography, x-ray computed; non-hodgkin's lymphoma; lymphoma; multiple sclerosis; nuclear magnetic resonance; brain neoplasm; middle age; human; male; article
Journal Title: Journal of Neuro-Oncology
Volume: 9
Issue: 2
ISSN: 0167-594X
Publisher: Springer  
Date Published: 1990-10-01
Start Page: 177
End Page: 181
Language: English
DOI: 10.1007/bf02427840
PUBMED: 2262803
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors