Primary CNS lymphoma: Managing patients with spontaneous and AIDS-related disease Journal Article


Authors: Deangelis, L. M.; Yahalom, J.; Rosenblum, M.; Posner, J. B.
Article Title: Primary CNS lymphoma: Managing patients with spontaneous and AIDS-related disease
Abstract: Primary central nervous system lymphoma, especially that associated with AIDS, is increasing in frequency. CT scan is virtually diagnostic when it shows multiple, hyperdense, diffusely enhancing periventricular lesions. Treatment often results in a complete remission, but the overall prognosis is poor. Surgery is important diagnostically, but resection is not helpful. Corticosteroids can produce significant shrinkage, and even disappearance, of PCNSL, but cranial radiation is still the cornerstone of therapy. The addition of chemotherapy to RT is promising in non-AIDS patients but still investigational.
Keywords: adult; aged; review; multimodality cancer therapy; combined modality therapy; brain tumor; brain neoplasms; lymphoma; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; middle age; human; male; female
Journal Title: Oncology (Norwalk)
Volume: 1
Issue: 6
ISSN: 0890-9091
Publisher: C M P Medica LLC * The Oncology Group  
Date Published: 1987-08-01
Start Page: 52
End Page: 59; Review 60-62
Language: English
PUBMED: 3079486
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 5 February 2021 -- Source: Scopus
Citation Impact
MSK Authors
  1. Joachim Yahalom
    625 Yahalom
  2. Marc Rosenblum
    424 Rosenblum
  3. Jerome B Posner
    211 Posner