Authors: | Deangelis, L. M.; Yahalom, J.; Rosenblum, M.; Posner, J. B. |
Article Title: | Primary CNS lymphoma: Managing patients with spontaneous and AIDS-related disease |
Abstract: | Primary central nervous system lymphoma, especially that associated with AIDS, is increasing in frequency. CT scan is virtually diagnostic when it shows multiple, hyperdense, diffusely enhancing periventricular lesions. Treatment often results in a complete remission, but the overall prognosis is poor. Surgery is important diagnostically, but resection is not helpful. Corticosteroids can produce significant shrinkage, and even disappearance, of PCNSL, but cranial radiation is still the cornerstone of therapy. The addition of chemotherapy to RT is promising in non-AIDS patients but still investigational. |
Keywords: | adult; aged; review; multimodality cancer therapy; combined modality therapy; brain tumor; brain neoplasms; lymphoma; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; middle age; human; male; female |
Journal Title: | Oncology (Norwalk) |
Volume: | 1 |
Issue: | 6 |
ISSN: | 0890-9091 |
Publisher: | C M P Medica LLC * The Oncology Group |
Date Published: | 1987-08-01 |
Start Page: | 52 |
End Page: | 59; Review 60-62 |
Language: | English |
PUBMED: | 3079486 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Export Date: 5 February 2021 -- Source: Scopus |