Bleomycin-induced pulmonary toxicity Journal Article


Authors: Jules-Elysee, K.; White, D. A.
Article Title: Bleomycin-induced pulmonary toxicity
Abstract: Bleomycin is recognized to cause an interstitial pneumonitis that can lead to fibrosis. Although its occurrence may be sporadic, some factors may increase the risk of such a pulmonary reaction. In this article the clinical setting and presentation, radiographic manifestations, pathologic findings, and the prognosis of bleomycin-induced interstitial fibrosis are described. Additionally, the role of pulmonary function tests in monitoring patients for toxicity is discussed.
Keywords: adult; aged; review; doxorubicin; lung toxicity; radiotherapy; oxygen therapy; cyclophosphamide; dexamethasone; vincristine; histology; coughing; dyspnea; fever; thorax pain; kidney function; bleomycin; thorax radiography; drug dose; lung fibrosis; pulmonary fibrosis; intravenous drug administration; blood gas; interstitial pneumonia; intramuscular drug administration; middle age; lung scintiscanning; subcutaneous drug administration; human; priority journal
Journal Title: Clinics in Chest Medicine
Volume: 11
Issue: 1
ISSN: 0272-5231
Publisher: Elsevier Inc.  
Date Published: 1990-03-01
Start Page: 1
End Page: 20
Language: English
PUBMED: 1691067
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
Citation Impact
MSK Authors
  1. Dorothy A White
    74 White