Extrapulmonary pneumocystis carinii infections Journal Article


Authors: Telzak, E. E.; Cote, R. J.; Gold, J. W. M.; Campbell, S. W.; Armstrong, D.
Article Title: Extrapulmonary pneumocystis carinii infections
Abstract: A case of disseminated infection with Pneumocystis carinii is presented, and the English-language literature is reviewed for cases of documented extrapulmonary infection with this organism. In this case - with P. carinii diffusely replacing the bone marrow and causing hepatic, adrenal, and glomerular tuft necrosis - the clinical illness and multiple-organ dysfunction attributed to disseminated P. carinii were more severe than had previously been described. Because the rate of extrapulmonary P. carinii infection found at autopsy in patients with AIDS is at least 2.5% at our institution, we caution against the routine use of aerosol rather than parenteral pentamidine for treatment of P. carinii pneumonia until additional data are available. © 1990 by The University of Chicago.
Keywords: adult; clinical article; preschool child; aged; clinical feature; review; case report; human immunodeficiency virus infection; bone marrow; risk factor; infant; acquired immunodeficiency syndrome; sarcoma, kaposi; autopsy; ganciclovir; pentamidine; protozoon; intravenous drug administration; opportunistic infections; multiple organ failure; opportunistic infection; fatality; parasitosis; mycoses; pneumocystis carinii; human; male; female; priority journal; inhalational drug administration; pneumonia, pneumocystis carinii
Journal Title: Clinical Infectious Diseases
Volume: 12
Issue: 3
ISSN: 1058-4838
Publisher: Oxford University Press  
Date Published: 1990-05-01
Start Page: 380
End Page: 386
Language: English
DOI: 10.1093/clinids/12.3.380
PUBMED: 2193343
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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MSK Authors
  1. Donald Armstrong
    222 Armstrong
  2. Jonathan W. M. Gold
    59 Gold
  3. Richard J. Cote
    25 Cote