Challenges after curative treatment for childhood cancer and long-term follow up of survivors Journal Article
| Authors: | Oeffinger, K. C.; Nathan, P. C.; Kremer, L. C. M. |
| Article Title: | Challenges after curative treatment for childhood cancer and long-term follow up of survivors |
| Abstract: | Childhood cancer survivors are at increased risk of serious morbidity, premature mortality, and diminished health status. Proactive and anticipatory risk-based health care of survivors and healthy lifestyles can reduce these risks. In this article, the authors first briefly discuss four common problems of survivors: neurocognitive dysfunction, cardiovascular disease, infertility and gonadal dysfunction, and psychosocial problems. Second, the authors discuss the concept of risk-based care, promote the use of recently developed evidence-based guidelines, describe current care in the United States, Canada, and the Netherlands, and articulate a model for shared survivor care that aims to optimize life long health of survivors and improve two-way communication between the cancer center and the primary care physician. © 2008 Elsevier Inc. All rights reserved. |
| Keywords: | osteosarcoma; adolescent; cancer chemotherapy; child; busulfan; prednisone; clinical trial; review; cisplatin; doxorubicin; heart left ventricle failure; antineoplastic agents; cancer radiotherapy; cytarabine; methotrexate; drug megadose; follow up; neoplasms; multiple cycle treatment; risk factors; combination chemotherapy; cyclophosphamide; melphalan; vincristine; stem cell transplantation; chlormethine; ifosfamide; procarbazine; thiotepa; acute lymphoblastic leukemia; childhood cancer; gonad dysfunction; hodgkin disease; ovary insufficiency; survivor; cancer survivor; survivors; nonhodgkin lymphoma; cardiovascular disease; cardiotoxicity; daunorubicin; long term care; aftercare; bleomycin; cognitive defect; corticosteroid; fertility; neurologic disease; coronary artery disease; primary medical care; androgen deficiency; social psychology; primary health care; male infertility; oligospermia; azoospermia; enalapril; carotid artery disease; early menopause; mantle field radiotherapy; epipodophyllotoxin |
| Journal Title: | Pediatric Clinics of North America |
| Volume: | 55 |
| Issue: | 1 |
| ISSN: | 0031-3955 |
| Publisher: | W.B. Saunders Co. |
| Date Published: | 2008-02-01 |
| Start Page: | 251 |
| End Page: | 273 |
| Language: | English |
| DOI: | 10.1016/j.pcl.2007.10.009 |
| PUBMED: | 18242324 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 23" - "Export Date: 17 November 2011" - "CODEN: PCNAA" - "Source: Scopus" |
